INCLISIRAN

Approval Year

Substance Class	Nucleic Acid
Nucleic Acid Type	siRNA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	UOW2C71PG5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ALN-60212

Preferred Name

English

INCLISIRAN

Official Name

English

RNA, (AM-SP-(2'-DEOXY-2'-FLUORO)C-SP-AM-(2'-DEOXY-2'-FLUORO)A-(2'-DEOXY-2'-FLUORO)A-(2'-DEOXY-2'-FLUORO)A-GM-(2'-DEOXY-2'-FLUORO)C-AM-(2'-DEOXY-2'-FLUORO)A-AM-(2'-DEOXY-2'-FLUORO)A-CM-(2'-DEOXY-2'-FLUORO)A-GM-(2'-DEOXY-2'-FLUORO)G-UM-(2'-DEOXY-2'-FLUORO)

Systematic Name

English

LEQVIO

Brand Name

English

inclisiran [INN]

Common Name

English

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Classification Tree

Code System

Code

Designated

FDA ORPHAN DRUG

618017

Showing 1 to 1 of 1 entries

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Code System

Code

Type

Description

DRUG BANK

DB14901

PRIMARY

INN

10268

PRIMARY

RXCUI

2588243

PRIMARY

NCI_THESAURUS

C170062

PRIMARY

USAN

EF-47

PRIMARY

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Subunit 0

Subunit 1

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Sugar	Site Range	Site Count
Deoxyribose (DNA)	1_11	1 / 45
2'-O-Methyl-Ribose	1_1-1_6;1_8;1_10;1_12-1_22;2_1;2_3;2_7;2_9;2_11;2_13;2_15;2_17;2_19-2_23	32 / 45
2'-Fluoro-Ribose	1_7;1_9;2_2;2_4-2_6;2_8;2_10;2_12;2_14;2_16;2_18	12 / 45