U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 12:02:27 GMT 2023
Edited
by admin
on Sat Dec 16 12:02:27 GMT 2023
Protein Type ENZYME
Protein Sub Type PROTEASE
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
LGW95S5DG1
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9
Common Name English
SUBTILISIN/KEXIN-LIKE PROTEASE PC9
Common Name English
PROPROTEIN CONVERTASE 9
Common Name English
PCSK9
Common Name English
NARC-1
Common Name English
NEURAL APOPTOSIS-REGULATED CONVERTASE 1
Common Name English
PC-9
Common Name English
Code System Code Type Description
FDA UNII
LGW95S5DG1
Created by admin on Sat Dec 16 12:02:28 GMT 2023 , Edited by admin on Sat Dec 16 12:02:28 GMT 2023
PRIMARY
UNIPROT
Q8NBP7
Created by admin on Sat Dec 16 12:02:28 GMT 2023 , Edited by admin on Sat Dec 16 12:02:28 GMT 2023
PRIMARY
From To
1_71 1_103
1_171 1_206
1_305 1_375
1_325 1_374
1_334 1_357
1_382 1_449
1_400 1_448
1_410 1_436
1_456 1_527
1_474 1_526
1_483 1_502
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_381
Related Record Type Details
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INHIBITOR OF EXPRESSION->TARGET
Inhibits translation by targeting PCSK9 for degradation
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
LIGAND->TARGET
INHIBITOR -> TARGET
BINDING
INHIBITOR -> TARGET
Antihypercholesterolemic
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR OF EXPRESSION->TARGET
SELECTIVELY INHIBITS RIBOSOMAL TRANSLATION
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR OF EXPRESSION->TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL