PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 17:52:15 GMT 2025` Edited by `admin` on `Tue Apr 01 17:52:15 GMT 2025`
Protein Type	ENZYME
Protein Sub Type	PROTEASE
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	LGW95S5DG1
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9

Common Name

English

NARC-1

Preferred Name

English

SUBTILISIN/KEXIN-LIKE PROTEASE PC9

Common Name

English

PROPROTEIN CONVERTASE 9

Common Name

English

PCSK9

Common Name

English

NEURAL APOPTOSIS-REGULATED CONVERTASE 1

Common Name

English

PC-9

Common Name

English

Code System Code Type Description

FDA UNII

LGW95S5DG1

Created by admin on Tue Apr 01 17:52:15 GMT 2025 , Edited by admin on Tue Apr 01 17:52:15 GMT 2025

PRIMARY

UNIPROT

Q8NBP7

Created by admin on Tue Apr 01 17:52:15 GMT 2025 , Edited by admin on Tue Apr 01 17:52:15 GMT 2025

PRIMARY

SMS_ID

300000014662

Created by admin on Tue Apr 01 17:52:15 GMT 2025 , Edited by admin on Tue Apr 01 17:52:15 GMT 2025

PRIMARY

From	To
1_71	1_103
1_171	1_206
1_305	1_375
1_325	1_374
1_334	1_357
1_382	1_449
1_400	1_448
1_410	1_436
1_456	1_527
1_474	1_526
1_483	1_502

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_381

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Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_536]		S		DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT	CHEMICAL