| Stereochemistry | ABSOLUTE |
| Molecular Formula | C22H17ClFN9O |
| Molecular Weight | 477.881 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=NC(N)=C(C#N)C(N[C@@H](C2CC2)C3=NC4=C(C(Cl)=CC=C4F)C(=O)N3C5=CC=CN=C5)=N1
InChI
InChIKey=XDSXYMOZKDUASY-INIZCTEOSA-N
InChI=1S/C22H17ClFN9O/c23-13-5-6-14(24)17-15(13)21(34)33(11-2-1-7-28-9-11)20(30-17)16(10-3-4-10)29-19-12(8-25)18(26)31-22(27)32-19/h1-2,5-7,9-10,16H,3-4H2,(H5,26,27,29,31,32)/t16-/m0/s1
| Molecular Formula | C22H17ClFN9O |
| Molecular Weight | 477.881 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
| 1.0 nM [IC50] | |||
| 770.0 nM [IC50] | |||
| 46.0 nM [IC50] | |||
| 51.0 nM [IC50] |
