HUMAN TRANSFORMING GROWTH FACTOR .BETA.-1

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 00:30:31 UTC 2023` Edited by `admin` on `Sat Dec 16 00:30:31 UTC 2023`
Protein Type	GROWTH FACTOR
Protein Sub Type	TGF .BETA. SUPERFAMILY
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	T7D25J14LT
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TRANSFORMING GROWTH FACTOR BETA-1

Preferred Name

English

HUMAN TRANSFORMING GROWTH FACTOR .BETA.-1

Common Name

English

RH-POLYPEPTIDE-22 [INCI]

Common Name

English

TRANSFORMING GROWTH FACTOR .BETA.-1

Common Name

English

TGF-.BETA. 1

Brand Name

English

TRANSFORMING GROWTH FACTOR BETA-1, HUMAN

Common Name

English

TRANSFORMING GROWTH FACTOR .BETA.-1, HUMAN

Common Name

English

RH-POLYPEPTIDE-22

Official Name

English

TRANSFORMING GROWTH FACTOR, BETA-1

Common Name

English

TGF-BETA-1

Common Name

English

TPX-6001

Code

English

VEXXON-TGFB1

Brand Name

English

TGF-β1

Common Name

English

TRANSFORMING GROWTH FACTOR BETA-1 (RECOMBINANT, E. COLI)

Common Name

English

TRANSFORMING GROWTH FACTOR .BETA.-1, NONGLYCOSYLATED

Common Name

English

Code System Code Type Description

FDA UNII

T7D25J14LT

Created by admin on Sat Dec 16 00:30:31 UTC 2023 , Edited by admin on Sat Dec 16 00:30:31 UTC 2023

PRIMARY

UNIPROT

P01137

Created by admin on Sat Dec 16 00:30:31 UTC 2023 , Edited by admin on Sat Dec 16 00:30:31 UTC 2023

PRIMARY

DAILYMED

T7D25J14LT

Created by admin on Sat Dec 16 00:30:31 UTC 2023 , Edited by admin on Sat Dec 16 00:30:31 UTC 2023

PRIMARY

NCI_THESAURUS

C1293

Created by admin on Sat Dec 16 00:30:31 UTC 2023 , Edited by admin on Sat Dec 16 00:30:31 UTC 2023

PRIMARY

RXCUI

1426465

Created by admin on Sat Dec 16 00:30:31 UTC 2023 , Edited by admin on Sat Dec 16 00:30:31 UTC 2023

PRIMARY

From	To
1_7	1_16
1_15	1_78
1_44	1_109
1_48	1_111
1_77	2_77
2_7	2_16
2_15	2_78
2_44	2_109
2_48	2_111

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					4AR6718OL0

LIGAND->TARGET

Amount:


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VECTOR->EXPRESSED PROTEIN

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INHIBITOR OF EXPRESSION->TARGET

Amount:


					375142VBIA

INHIBITOR -> TARGET

Amount:


					FT06VU379M

TGF-BETA RECEPTOR TYPE-1

TARGET -> AGONIST

Comments:

TGFB1, TGFB2 and TGFB3 homodimeric ligands assemble a functional receptor composed of two TGFBR1 and TGFBR2 heterodimers to form a ligand-receptor heterohexamer.

Amount:


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SHP-627

INHIBITOR -> TARGET

Interaction Type:

IN-VITRO

Amount:


					O5QC3YP0M7

INHIBITOR OF EXPRESSION->TARGET

Amount:


					4AR6718OL0

INHIBITOR -> TARGET

Amount:


					9TS3G2M6LS

INHIBITOR -> TARGET

Amount:


					6EX05GL2VK

AVID-200

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					W2OR26S7UE

INHIBITOR -> TARGET

Amount:

Related Record Type Details


					T7D25J14LT

HUMAN TRANSFORMING GROWTH FACTOR .BETA.-1

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL