TGF-BETA RECEPTOR TYPE-1

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 23:27:00 GMT 2025` Edited by `admin` on `Tue Apr 01 23:27:00 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	FT06VU379M
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TGF-BETA RECEPTOR TYPE-1

Common Name

English

ACTIVIN A RECEPTOR TYPE II-LIKE PROTEIN KINASE OF 53KD

Preferred Name

English

TGF-BETA TYPE I RECEPTOR

Common Name

English

ALK5

Common Name

English

ACTIVIN RECEPTOR-LIKE KINASE 5

Common Name

English

TGF-BETA RECEPTOR TYPE I

Common Name

English

SKR4

Common Name

English

SERINE/THREONINE-PROTEIN KINASE RECEPTOR R4

Common Name

English

TBETAR-I

Common Name

English

TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I

Common Name

English

TGFBR1

Common Name

English

Code System Code Type Description

UNIPROT

P36897

Created by admin on Tue Apr 01 23:27:00 GMT 2025 , Edited by admin on Tue Apr 01 23:27:00 GMT 2025

PRIMARY

FDA UNII

FT06VU379M

Created by admin on Tue Apr 01 23:27:00 GMT 2025 , Edited by admin on Tue Apr 01 23:27:00 GMT 2025

PRIMARY

From	To
1_3	1_21
1_5	1_8
1_15	1_38
1_53	1_67
1_68	1_73

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_12

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Comments:

TGFB1, TGFB2 and TGFB3 homodimeric ligands assemble a functional receptor composed of two TGFBR1 and TGFBR2 heterodimers to form a ligand-receptor heterohexamer.

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_132] [1_154] [1_156] [1_158]		S		DEXFOSFOSERINE	VI4F0K069V
AMINO ACID SUBSTITUTION	[1_152] [1_153]		T		THREONINE PHOSPHATE	3L4WX7B1EI

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL