Pixofisiran

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 14:44:37 UTC 2023` Edited by `admin` on `Sat Dec 16 14:44:37 UTC 2023`
Nucleic Acid Type	siRNA
Nucleic Acid Subtype
Sequence Type	COMPLETE
Record UNII	O5QC3YP0M7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Pixofisiran

Official Name

English

TGF-.BETA.1 SI-RNA FREE ACID COMPONENT OF COTSIRANIB

Common Name

English

HIMTF-25-2 FREE ACID

Common Name

English

pixofisiran [INN]

Common Name

English

STP-705 COMPONENT TGF-.BETA.1 SI-RNA FREE ACID

Common Name

English

RNA, (A-G-A-A-G-U-U-G-G-C-A-U-G-G-U-A-G-C-C-C-U-U-G-G-G), COMPLEX WITH RNA (C-C-C-A-A-G-G-G-C-U-A-C-C-A-U-G-C-C-A-A-C-U-U-C-U) (1:1)

Common Name

English

COTSIRANIB TGF-.BETA.1 SI-RNA FREE ACID COMPONENT

Common Name

English

Code System Code Type Description

INN

11789

Created by admin on Sat Dec 16 14:44:38 UTC 2023 , Edited by admin on Sat Dec 16 14:44:38 UTC 2023

PRIMARY

FDA UNII

O5QC3YP0M7

Created by admin on Sat Dec 16 14:44:38 UTC 2023 , Edited by admin on Sat Dec 16 14:44:38 UTC 2023

PRIMARY

CAS

1152798-48-5

Created by admin on Sat Dec 16 14:44:38 UTC 2023 , Edited by admin on Sat Dec 16 14:44:38 UTC 2023

PRIMARY

NCI_THESAURUS

C184821

Created by admin on Sat Dec 16 14:44:38 UTC 2023 , Edited by admin on Sat Dec 16 14:44:38 UTC 2023

PRIMARY

Sugar	Site Range	Site Count
D-Ribose (RNA)	1_1-1_25;2_1-2_25	50 / 50

Linkage	Site Range	Site Count
Phosphate	1_2-1_25;2_2-2_25	48 / 48

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ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL