TYROSINE-PROTEIN KINASE BTK C481S (IBRUTINIB RESISTANT MUTANT)

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 21:52:04 GMT 2025` Edited by `admin` on `Tue Apr 01 21:52:04 GMT 2025`
Protein Type	ENZYME
Protein Sub Type	KINASE
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	T59477XR5I
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BTK C481S

Preferred Name

English

TYROSINE-PROTEIN KINASE BTK C481S (IBRUTINIB RESISTANT MUTANT)

Common Name

English

TYROSINE-PROTEIN KINASE BTK C481S MUTANT (METHIONINE INCLUDED IN NUMBERING)

Common Name

English

TYROSINE-PROTEIN KINASE BTK C480S MUTANT

Common Name

English

Code System Code Type Description

FDA UNII

T59477XR5I

Created by admin on Tue Apr 01 21:52:04 GMT 2025 , Edited by admin on Tue Apr 01 21:52:04 GMT 2025

PRIMARY

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Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_20] [1_54] [1_622] [1_648]	SITE_SPECIFIC			DEXFOSFOSERINE	VI4F0K069V
METAL_BINDING	[1_142] [1_153] [1_154] [1_164]	SITE_SPECIFIC			ZINC CATION	13S1S8SF37

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL