PIRTOBRUTINIB

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H21F4N5O3
Molecular Weight	479.4275
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=C(C=C(F)C=C1)C(=O)NCC2=CC=C(C=C2)C3=NN([C@@H](C)C(F)(F)F)C(N)=C3C(N)=O

InChI

InChIKey=FWZAWAUZXYCBKZ-NSHDSACASA-N

InChI=1S/C22H21F4N5O3/c1-11(22(24,25)26)31-19(27)17(20(28)32)18(30-31)13-5-3-12(4-6-13)10-29-21(33)15-9-14(23)7-8-16(15)34-2/h3-9,11H,10,27H2,1-2H3,(H2,28,32)(H,29,33)/t11-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C22H21F4N5O3
Molecular Weight	479.4275
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 14:17:43 GMT 2023` Edited by `admin` on `Sat Dec 16 14:17:43 GMT 2023`
Record UNII	JNA39I7ZVB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PIRTOBRUTINIB

Official Name

English

1H-PYRAZOLE-4-CARBOXAMIDE, 5-AMINO-3-(4-(((5-FLUORO-2-METHOXYBENZOYL)AMINO)METHYL)PHENYL)-1-((1S)-2,2,2-TRIFLUORO-1-METHYLETHYL)-

Systematic Name

English

LY3527727

Code

English

JAYPIRCA

Brand Name

English

5-AMINO-3-(4-((5-FLUORO-2-METHOXYBENZAMIDO)METHYL)PHENYL)-1-((2S)-1,1,1-TRIFLUOROPROPAN-2-YL)-1H-PYRAZOLE-4-CARBOXAMIDE

Systematic Name

English

LOXO-305

Code

English

PIRTOBRUTINIB [JAN]

Common Name

English

LY-3527727

Code

English

(S)-5-AMINO-3-(4-((5-FLUORO-2-METHOXYBENZAMIDO)METHYL)PHENYL)-1-(1,1,1-TRIFLUOROPROPAN-2-YL)-1H-PYRAZOLE-4-CARBOXAMIDE

Systematic Name

English

RXC-005

Code

English

PIRTOBRUTINIB [USAN]

Common Name

English

pirtobrutinib [INN]

Common Name

English

Pirtobrutinib [WHO-DD]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

758120