ZICRONAPINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H27ClN2
Molecular Weight	354.916
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ZICRONAPINE

Structure Search

SMILES

CN1CCN(CC1(C)C)[C@@H]2C[C@H](C3=C2C=C(Cl)C=C3)C4=CC=CC=C4

InChI

InChIKey=BYPMJBXPNZMNQD-PZJWPPBQSA-N

InChI=1S/C22H27ClN2/c1-22(2)15-25(12-11-24(22)3)21-14-19(16-7-5-4-6-8-16)18-10-9-17(23)13-20(18)21/h4-10,13,19,21H,11-12,14-15H2,1-3H3/t19-,21+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C22H27ClN2
Molecular Weight	354.916
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://clinicaltrials.gov/ct2/show/NCT01295372 | https://investor.lundbeck.com/news-releases/news-release-details/clinical-phase-iii-programme-commenced-zicronapine?releaseid=608573

Zicronapine (formerly known as Lu 31-130), an oral antipsychotic that was studied for the treatment of schizophrenia. The drug was used in a phase III clinical trial.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed

Patents

Patents

Sample Use Guides

In Vivo Use Guide

7.5 mg/day

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:59:52 UTC 2023` Edited by `admin` on `Fri Dec 15 15:59:52 UTC 2023`
Record UNII	QZV11V7G6A
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ZICRONAPINE

Official Name

English

LU-31-130

Code

English

Zicronapine [WHO-DD]

Common Name

English

LU 31-130

Code

English

zicronapine [INN]

Common Name

English

ZICRONAPINE [USAN]

Common Name

English

4-[(1R,3S)-6-Chloro-3-phenyl-2,3-dihydro-1H-inden-1-yl]-1,2,2-trimethylpiperazine

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29710

Created by admin on Fri Dec 15 15:59:52 UTC 2023 , Edited by admin on Fri Dec 15 15:59:52 UTC 2023

Code System Code Type Description

USAN

ZZ-30

Created by admin on Fri Dec 15 15:59:52 UTC 2023 , Edited by admin on Fri Dec 15 15:59:52 UTC 2023

PRIMARY

SMS_ID

100000175013

Created by admin on Fri Dec 15 15:59:52 UTC 2023 , Edited by admin on Fri Dec 15 15:59:52 UTC 2023

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NCI_THESAURUS

C152950

Created by admin on Fri Dec 15 15:59:52 UTC 2023 , Edited by admin on Fri Dec 15 15:59:52 UTC 2023

PRIMARY

INN

9050

Created by admin on Fri Dec 15 15:59:52 UTC 2023 , Edited by admin on Fri Dec 15 15:59:52 UTC 2023

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ChEMBL

CHEMBL3039528

Created by admin on Fri Dec 15 15:59:52 UTC 2023 , Edited by admin on Fri Dec 15 15:59:52 UTC 2023

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WIKIPEDIA

ZICRONAPINE

Created by admin on Fri Dec 15 15:59:52 UTC 2023 , Edited by admin on Fri Dec 15 15:59:52 UTC 2023

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DRUG BANK

DB12188

Created by admin on Fri Dec 15 15:59:52 UTC 2023 , Edited by admin on Fri Dec 15 15:59:52 UTC 2023

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FDA UNII

QZV11V7G6A

Created by admin on Fri Dec 15 15:59:52 UTC 2023 , Edited by admin on Fri Dec 15 15:59:52 UTC 2023

PRIMARY

EPA CompTox

DTXSID30168849

Created by admin on Fri Dec 15 15:59:52 UTC 2023 , Edited by admin on Fri Dec 15 15:59:52 UTC 2023

PRIMARY

PUBCHEM

11465618

Created by admin on Fri Dec 15 15:59:52 UTC 2023 , Edited by admin on Fri Dec 15 15:59:52 UTC 2023

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CAS

170381-16-5

Created by admin on Fri Dec 15 15:59:52 UTC 2023 , Edited by admin on Fri Dec 15 15:59:52 UTC 2023

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					Q7H2LD73H5

ZICRONAPINE SUCCINATE

SALT/SOLVATE -> PARENT

Amount:


					54202V7DRJ

D(1A) DOPAMINE RECEPTOR

TARGET -> INHIBITOR

Amount:


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LABELED -> NON-LABELED

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5-HYDROXYTRYPTAMINE RECEPTOR 2A

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					19GBD6T9L7

D(2) DOPAMINE RECEPTOR

TARGET -> INHIBITOR

Amount:


					354Q3TY534

ZICRONAPINE FUMARATE

SALT/SOLVATE -> PARENT

Amount:

Related Record Type Details


					QZV11V7G6A

ACTIVE MOIETY

Amount: