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Details

Stereochemistry ACHIRAL
Molecular Formula F
Molecular Weight 18.9984
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge -1

SHOW SMILES / InChI
Structure of FLUORIDE ION

SMILES

[F-]

InChI

InChIKey=KRHYYFGTRYWZRS-UHFFFAOYSA-M
InChI=1S/FH/h1H/p-1

HIDE SMILES / InChI

Molecular Formula FH
Molecular Weight 20.0063
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Calcium iodide (chemical formula CaI2) is the ionic compound of calcium and iodine, used in cat food as a source of iodine This colourless deliquescent solid is a salt that is highly soluble in water. Calcium iodide properties are similar to those for related salts, such as calcium chloride. Calcium iodide is also used in photography.

CNS Activity

Originator

Sources: Helvetica Odontologica Acta (1962), 6, (1), 15-20.https://www.ncbi.nlm.nih.gov/pubmed/16960820

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
elmex

Approved Use

Unknown
Primary
Unknown

Approved Use

Unknown
Palliative
Unknown

Approved Use

Unknown
Palliative
Unknown

Approved Use

Unknown
Primary
Unknown

Approved Use

Hypocalcemia, chronic (treatment) — Oral calcium supplements provide a source of calcium ion for treating calcium depletion occurring in conditions such as chronic hypoparathyroidism, pseudohypoparathyroidism, osteomalacia, rickets, chronic renal failure, and hypocalcemia secondary to the administration of anticonvulsant medications. When chronic hypocalcemia is due to vitamin D deficiency, oral calcium salts may be administered concomitantly with vitamin D analogs. However, calcium phosphate should not be used in patients with hypoparathyroidism or renal failure, since phosphate levels may be too high and giving more phosphate would exacerbate the condition. Calcium supplements should not be used in hyperparathyroidism, unless the need for a calcium supplement is high and the patient is carefully monitored. For treatment of hypocalcemia, supplementation is preferred
PubMed

PubMed

TitleDatePubMed
Studies on the calcemic effect of intravenous secretin in humans.
1975 Jun
Endothelin-induced changes of secondary messengers in cultured corneal endothelial cells.
2001 Aug
Metal ion-independent association of factor VIII subunits and the roles of calcium and copper ions for cofactor activity and inter-subunit affinity.
2001 Aug 28
Potent inhibition of NFAT activation and T cell cytokine production by novel low molecular weight pyrazole compounds.
2001 Dec 21
Functional expression and characterization of a voltage-gated CaV1.3 (alpha1D) calcium channel subunit from an insulin-secreting cell line.
2001 Jul
Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities.
2001 Nov
Activating mutations of the calcium-sensing receptor: management of hypocalcemia.
2001 Nov
Regression of ventral striatum hypometabolism after calcium/calcitriol therapy in paroxysmal kinesigenic choreoathetosis due to idiopathic primary hypoparathyroidism.
2001 Nov
Molecular cloning and functional characterization of murine cysteinyl-leukotriene 1 (CysLT(1)) receptors.
2001 Nov 1
Hypoxia-induced regulation of MAPK phosphatase-1 as identified by subtractive suppression hybridization and cDNA microarray analysis.
2001 Nov 30
Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide.
2001 Oct
Microarray analysis of differential gene expression in lead-exposed astrocytes.
2001 Oct 1
Phosphoinositide 3-kinase isoforms selectively couple receptors to vascular L-type Ca(2+) channels.
2001 Oct 12
Replacement of the muscle-specific sarcoplasmic reticulum Ca(2+)-ATPase isoform SERCA2a by the nonmuscle SERCA2b homologue causes mild concentric hypertrophy and impairs contraction-relaxation of the heart.
2001 Oct 26
Regional differences in functional receptor distribution and calcium mobilization in the intact human lens.
2001 Sep
Heterologous expression of the Na(+),K(+)-ATPase gamma subunit in Xenopus oocytes induces an endogenous, voltage-gated large diameter pore.
2001 Sep 1
A diacylglycerol-activated Ca2+ channel in PC12 cells (an adrenal chromaffin cell line) correlates with expression of the TRP-6 (transient receptor potential) protein.
2001 Sep 15
Ameliorative effect of vasopressin-(4-9) through vasopressin V(1A) receptor on scopolamine-induced impairments of rat spatial memory in the eight-arm radial maze.
2001 Sep 7
Interaction of intravenous anesthetics with recombinant human M1-M3 muscarinic receptors expressed in chinese hamster ovary cells.
2002 Dec
Mediation of unusually high concentrations of 1,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal 1alpha-hydroxylase gene.
2002 Feb
Characterization of the bone-resorptive effect of interleukin-11 in cultured mouse calvarial bones.
2002 Jul
Delayed asystolic cardiac arrest after diltiazem overdose; resuscitation with high dose intravenous calcium.
2002 Jul
Transcriptional induction of CYP1A1 by oltipraz in human Caco-2 cells is aryl hydrocarbon receptor- and calcium-dependent.
2002 Jul 5
Human kidney diamine oxidase: heterologous expression, purification, and characterization.
2002 Jun
Expression of functional CCR and CXCR chemokine receptors in podocytes.
2002 Jun 15
Investigation of a functional requirement for isoprenylation by the human prostacyclin receptor.
2002 Mar
Hypertension-related intermyocyte junction remodelling is associated with a higher incidence of low-K(+)-induced lethal arrhythmias in isolated rat heart.
2002 Mar
Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice.
2002 Mar 15
Diacylglycerol activates the influx of extracellular cations in T-lymphocytes independently of intracellular calcium-store depletion and possibly involving endogenous TRP6 gene products.
2002 May 15
Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit.
2002 Sep
Inhibition of peroxisome proliferator-activated receptor (PPAR)-mediated keratinocyte differentiation by lipoxygenase inhibitors.
2002 Sep 15
Effects of endothelin B receptor agonists on amyloid beta protein (25-35)-induced neuronal cell death.
2002 Sep 6
A critical interplay between Ca2+ inhibition and activation by Mg2+ of AC5 revealed by mutants and chimeric constructs.
2002 Sep 6
Mechanism of enhanced calcium sensitivity and alpha 2-AR vasoreactivity in chronic NOS inhibition hypertension.
2003 Jan
Epidemiology of 377 patients with chemical burns in Guangdong province.
2004 Sep
[Prevention of osteoporosis by foods and dietary supplements. Bioavailability of milk micellar calcium phosphate].
2006 Oct
Henri Moissan: winner of the Nobel Prize for Chemistry 1906.
2006 Oct 20
Successful extracorporeal life support after potentially fatal pulmonary oedema caused by inhalation of nitric and hydrofluoric acid fumes.
2007 Oct
Dietary calcium source influences body composition, glucose metabolism and hormone levels in a mouse model of postmenopausal obesity.
2009 Jul-Aug
A combination of calcium phosphate and probiotics beneficially influences intestinal lactobacilli and cholesterol metabolism in humans.
2012 Apr
Sensitivity of human dental pulp cells to eighteen chemical agents used for endodontic treatments in dentistry.
2013 Jan
Effect of calcium phosphate and vitamin D₃ supplementation on bone remodelling and metabolism of calcium, phosphorus, magnesium and iron.
2014 Jan 17
Long-term remineralizing effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on early caries lesions in vivo: a systematic review.
2014 Jul
Oleylamine as a beneficial agent for the synthesis of CoFe₂O₄ nanoparticles with potential biomedical uses.
2014 May 7
Efficacy and safety of inhaled calcium lactate PUR118 in the ozone challenge model--a clinical trial.
2015 Aug 12
Cytotoxicity of organic surface coating agents used for nanoparticles synthesis and stability.
2015 Jun
Dietary interventions for mineral and bone disorder in people with chronic kidney disease.
2015 Sep 16
Lactose behaviour in the presence of lactic acid and calcium.
2016 Aug
Allergic contact cheilitis caused by olaflur in toothpaste.
2017 Jan
Effects of ultrasound treatment on physico-chemical, functional properties and antioxidant activity of whey protein isolate in the presence of calcium lactate.
2018 Mar
Patents

Patents

Sample Use Guides

toxicity in mice: LD50 = 888 mg/kg
Route of Administration: Intraperitoneal
Cytotoxicity study: it was explored the cytotoxicity of the coating agent, Oleylamine in two cell lines, human epidermal keratinocyte (HaCaT) and lung fibroblast (CRL-1490) cells, at surface coating agent concentrations of 3, 10, 30, and 100 μM. Two exposure time points, 2 h, and 24 h were employed for the study. Oleylamine, is highly toxic, leading to almost 100% cell death.
Substance Class Chemical
Created
by admin
on Sat Jun 26 09:27:14 UTC 2021
Edited
by admin
on Sat Jun 26 09:27:14 UTC 2021
Record UNII
Q80VPU408O
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FLUORIDE ION
Common Name English
FLUORINE ION(F1-)
Common Name English
FLUORINE ION
Common Name English
FLURORIDE-ION
Common Name English
FLUORIDE ION(1-)
Common Name English
FLUORIDE
VANDF  
Systematic Name English
FLUORIDE [VANDF]
Common Name English
PERFLUORIDE
Common Name English
Classification Tree Code System Code
WHO-ATC A12CD51
Created by admin on Sat Jun 26 09:27:15 UTC 2021 , Edited by admin on Sat Jun 26 09:27:15 UTC 2021
NCI_THESAURUS C68252
Created by admin on Sat Jun 26 09:27:15 UTC 2021 , Edited by admin on Sat Jun 26 09:27:15 UTC 2021
DSLD 2968 (Number of products:4)
Created by admin on Sat Jun 26 09:27:15 UTC 2021 , Edited by admin on Sat Jun 26 09:27:15 UTC 2021
WHO-VATC QA12CD51
Created by admin on Sat Jun 26 09:27:15 UTC 2021 , Edited by admin on Sat Jun 26 09:27:15 UTC 2021
FDA ORPHAN DRUG 143901
Created by admin on Sat Jun 26 09:27:15 UTC 2021 , Edited by admin on Sat Jun 26 09:27:15 UTC 2021
Code System Code Type Description
PUBCHEM
28179
Created by admin on Sat Jun 26 09:27:15 UTC 2021 , Edited by admin on Sat Jun 26 09:27:15 UTC 2021
PRIMARY
DRUG BANK
DB11257
Created by admin on Sat Jun 26 09:27:15 UTC 2021 , Edited by admin on Sat Jun 26 09:27:15 UTC 2021
PRIMARY
CAS
16984-48-8
Created by admin on Sat Jun 26 09:27:15 UTC 2021 , Edited by admin on Sat Jun 26 09:27:15 UTC 2021
PRIMARY
NCI_THESAURUS
C28149
Created by admin on Sat Jun 26 09:27:15 UTC 2021 , Edited by admin on Sat Jun 26 09:27:15 UTC 2021
PRIMARY
EPA CompTox
16984-48-8
Created by admin on Sat Jun 26 09:27:15 UTC 2021 , Edited by admin on Sat Jun 26 09:27:15 UTC 2021
PRIMARY
FDA UNII
Q80VPU408O
Created by admin on Sat Jun 26 09:27:15 UTC 2021 , Edited by admin on Sat Jun 26 09:27:15 UTC 2021
PRIMARY
RXCUI
196213
Created by admin on Sat Jun 26 09:27:15 UTC 2021 , Edited by admin on Sat Jun 26 09:27:15 UTC 2021
PRIMARY RxNorm
EVMPD
SUB21927
Created by admin on Sat Jun 26 09:27:15 UTC 2021 , Edited by admin on Sat Jun 26 09:27:15 UTC 2021
PRIMARY
WIKIPEDIA
FLUORIDE
Created by admin on Sat Jun 26 09:27:15 UTC 2021 , Edited by admin on Sat Jun 26 09:27:15 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> METABOLITE TOXIC
METABOLITE TO PARENT DRUG RATIO
PLASMA; URINE
PARENT -> METABOLITE
Related Record Type Details
PARENT -> IMPURITY
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ACTIVE MOIETY