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Details

Stereochemistry ACHIRAL
Molecular Formula F
Molecular Weight 18.9984
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge -1

SHOW SMILES / InChI
Structure of FLUORIDE ION

SMILES

[F-]

InChI

InChIKey=KRHYYFGTRYWZRS-UHFFFAOYSA-M
InChI=1S/FH/h1H/p-1

HIDE SMILES / InChI

Molecular Formula FH
Molecular Weight 20.0063
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.drugs.com/international/olaflur.html | https://www.ncbi.nlm.nih.gov/pubmed/15528912 | https://clinicaltrials.gov/ct2/show/record/NCT00268138 | https://www.old.health.gov.il/units/pharmacy/trufot/alonim/4872.pdf

Oleylamine (or oleamine) is a versatile and flexible reagent in synthesis as well as the desired surface ligand for the synthesis of nanoparticles. This compound is rather toxic to mammalian organism.

CNS Activity

Originator

Sources: Helvetica Odontologica Acta (1962), 6, (1), 15-20.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
elmex

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
An improved method for emergent decontamination of ocular and dermal hydrofluoric acid splashes.
2004 Aug
Epidemiology of 377 patients with chemical burns in Guangdong province.
2004 Sep
Successful extracorporeal life support after potentially fatal pulmonary oedema caused by inhalation of nitric and hydrofluoric acid fumes.
2007 Oct
Sensitivity of human dental pulp cells to eighteen chemical agents used for endodontic treatments in dentistry.
2013 Jan
Oleylamine as a beneficial agent for the synthesis of CoFe₂O₄ nanoparticles with potential biomedical uses.
2014 May 7
Cytotoxicity of organic surface coating agents used for nanoparticles synthesis and stability.
2015 Jun
Allergic contact cheilitis caused by olaflur in toothpaste.
2017 Jan
Patents

Patents

Sample Use Guides

Brushing your teeth thoroughly with the preparation once a week. Just use elmex dental gel using a regular toothbrush for a period of 2-3 minutes, rinse normally. The total time of application (brushing and residence time) should not exceed five minutes.
Route of Administration: Dental
In Vitro Use Guide
The outer 50-100 mkm of the surface of freshly extracted human incisors was removed by grinding and polishing, thus removing not only the pellicle from the surface but also the outer mineral layer, which in general shows the greatest variation in chemical constituents. Amine fluoride 297 (AmF 297) were dissolved in distilled water. After adsorption of aminefluorides on the enamel for 2 min at a volume to area ratio of 25 cm3/cm2, the enamel surfaces were rinsed with distilled water and allowed to dry for several hours at room temperature in an enclosed chamber. Subsequently adsorbed layer thicknesses were determined by ellipsometry, and surface free energies were calculated from contact angle data.
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:52:39 UTC 2023
Edited
by admin
on Fri Dec 15 16:52:39 UTC 2023
Record UNII
Q80VPU408O
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FLUORIDE ION
Common Name English
FLUORINE ION(F1-)
Common Name English
FLUORINE ION
Common Name English
FLURORIDE-ION
Common Name English
FLUORIDE ION(1-)
Common Name English
FLUORIDE
VANDF  
Systematic Name English
FLUORIDE [VANDF]
Common Name English
PERFLUORIDE
Common Name English
Classification Tree Code System Code
WHO-ATC A12CD51
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
NCI_THESAURUS C68252
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
DSLD 2968 (Number of products:4)
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
WHO-VATC QA12CD51
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
FDA ORPHAN DRUG 143901
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
Code System Code Type Description
CHEBI
17051
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
PRIMARY
PUBCHEM
28179
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
PRIMARY
DAILYMED
Q80VPU408O
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
PRIMARY
DRUG BANK
DB11257
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
PRIMARY
CAS
16984-48-8
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
PRIMARY
NCI_THESAURUS
C28149
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
PRIMARY
EPA CompTox
DTXSID9049617
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
PRIMARY
FDA UNII
Q80VPU408O
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
PRIMARY
CHEBI
29228
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
PRIMARY
RXCUI
196213
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
PRIMARY RxNorm
EVMPD
SUB21927
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
PRIMARY
WIKIPEDIA
FLUORIDE
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
PRIMARY
SMS_ID
100000088222
Created by admin on Fri Dec 15 16:52:40 UTC 2023 , Edited by admin on Fri Dec 15 16:52:40 UTC 2023
PRIMARY
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