ALPHA-1B ADRENERGIC RECEPTOR

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Jun 26 23:29:54 UTC 2021` Edited by `admin` on `Sat Jun 26 23:29:54 UTC 2021`
Protein Type	RECEPTOR
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	Q7A4S7HOP4
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ALPHA-1B ADRENERGIC RECEPTOR

Common Name

English

ALPHA-1B ADRENORECEPTOR

Common Name

English

Code System Code Type Description

FDA UNII

Q7A4S7HOP4

Created by admin on Sat Jun 26 23:29:56 UTC 2021 , Edited by admin on Sat Jun 26 23:29:56 UTC 2021

PRIMARY

From	To
1_118	1_195

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_10
N	1_24
N	1_29
N	1_34

Related Record Type Details


					J7A92W69L7

DROXIDOPA

AGONIST -> TARGET


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DOXAZOSIN

INHIBITOR -> TARGET


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INHIBITOR -> TARGET


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DOXAZOSIN

AGONIST -> TARGET


					2J3YBM1K8C

INHIBITOR -> TARGET


					YKH834O4BH

AGONIST -> TARGET


					G3P28OML5I

INHIBITOR -> TARGET

Qualification:

Ki

Amount:


					E9H51OIT2B

WB-4101

INHIBITOR -> TARGET


					8L5014XET7

TERAZOSIN

INHIBITOR -> TARGET


					6YE7PBM15H

MIDODRINE

AGONIST -> TARGET


					5RNZ8GJO7K

INHIBITOR -> TARGET


					XM03YJ541D

PRAZOSIN

INHIBITOR -> TARGET


					90347YTW5F

ALFUZOSIN

AGONIST -> TARGET


					X4W3ENH1CV

AGONIST -> TARGET


					90347YTW5F

ALFUZOSIN

INHIBITOR -> TARGET


					CUZ39LUY82

SILODOSIN

INHIBITOR->OFF-TARGET

Comments:

Selectivity of silodosin determined in cloned human ?1-adrenergic receptor (?1-AR) subtypes in cultured Chinese hamster ovary cells.

Qualification:

Ki

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT	CHEMICAL