TRIFLUOMEPRAZINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H21F3N2S
Molecular Weight	366.444
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TRIFLUOMEPRAZINE

Structure Search

SMILES

CC(CN(C)C)CN1C2=CC=CC=C2SC3=CC=C(C=C13)C(F)(F)F

InChI

InChIKey=ILBBYVOOXMPNTM-UHFFFAOYSA-N

InChI=1S/C19H21F3N2S/c1-13(11-23(2)3)12-24-15-6-4-5-7-17(15)25-18-9-8-14(10-16(18)24)19(20,21)22/h4-10,13H,11-12H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C19H21F3N2S
Molecular Weight	366.444
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://books.google.ru/books?id=0vXTBwAAQBAJ&pg=PA1236&lpg=PA1236&dq=Nortran retrieved from Dictionary of drugs: Chemical data, structures and bibliographies, edited by J. Elks, p.1236
Curator's Comment: Description was created based on several sources, including https://myhealthbox.eu/en_us/drug/nortrantablets/2391535

Trifluomeprazine is a sedative and hypnotic, it was used in veterinary medicine under the brand name Nortran. Withdrawn from the market.

CNS Activity

Originator

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Anxiety 275 Sources: https://cdn.loc.gov/service/ll/fedreg/fr054/fr054008/fr054008.pdf	Primary		Approved 8583	NORTRAN TABLETS Approved Use Nortran (trifluomeprazine) Tablets were intended for use in dogs for tranquilization Launch Date 1972

PubMed

PubMed

Title	Date	PubMed
Standardised thin-layer chromatographic systems for the identification of drugs and poisons.	1982-10	6758633

Patents

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:02:25 GMT 2025` Edited by `admin` on `Mon Mar 31 18:02:25 GMT 2025`
Record UNII	OF4T2241HQ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TRIFLUOMEPRAZINE

Official Name

English

TRIFLUOMEPRAZINE [MI]

Preferred Name

English

trifluomeprazine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29756

Created by admin on Mon Mar 31 18:02:25 GMT 2025 , Edited by admin on Mon Mar 31 18:02:25 GMT 2025

Code System Code Type Description

SMS_ID

100000077724

Created by admin on Mon Mar 31 18:02:25 GMT 2025 , Edited by admin on Mon Mar 31 18:02:25 GMT 2025

PRIMARY

FDA UNII

OF4T2241HQ

Created by admin on Mon Mar 31 18:02:25 GMT 2025 , Edited by admin on Mon Mar 31 18:02:25 GMT 2025

PRIMARY

ChEMBL

CHEMBL1717401

Created by admin on Mon Mar 31 18:02:25 GMT 2025 , Edited by admin on Mon Mar 31 18:02:25 GMT 2025

PRIMARY

EVMPD

SUB11287MIG

Created by admin on Mon Mar 31 18:02:25 GMT 2025 , Edited by admin on Mon Mar 31 18:02:25 GMT 2025

PRIMARY

EPA CompTox

DTXSID7048247

Created by admin on Mon Mar 31 18:02:25 GMT 2025 , Edited by admin on Mon Mar 31 18:02:25 GMT 2025

PRIMARY

MERCK INDEX

m11115

Created by admin on Mon Mar 31 18:02:25 GMT 2025 , Edited by admin on Mon Mar 31 18:02:25 GMT 2025

PRIMARY

Merck Index

NCI_THESAURUS

C76951

Created by admin on Mon Mar 31 18:02:25 GMT 2025 , Edited by admin on Mon Mar 31 18:02:25 GMT 2025

PRIMARY

CAS

2622-37-9

Created by admin on Mon Mar 31 18:02:25 GMT 2025 , Edited by admin on Mon Mar 31 18:02:25 GMT 2025

PRIMARY

INN

3800

Created by admin on Mon Mar 31 18:02:25 GMT 2025 , Edited by admin on Mon Mar 31 18:02:25 GMT 2025

PRIMARY

PUBCHEM

72136

Created by admin on Mon Mar 31 18:02:25 GMT 2025 , Edited by admin on Mon Mar 31 18:02:25 GMT 2025

PRIMARY

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ACTIVE MOIETY