TRIFLUOMEPRAZINE MALEATE

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H21F3N2S.C4H4O4
Molecular Weight	482.516
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)\C=C/C(O)=O.CC(CN(C)C)CN1C2=CC=CC=C2SC3=C1C=C(C=C3)C(F)(F)F

InChI

InChIKey=MRRIMVLRWWYKTQ-BTJKTKAUSA-N

InChI=1S/C19H21F3N2S.C4H4O4/c1-13(11-23(2)3)12-24-15-6-4-5-7-17(15)25-18-9-8-14(10-16(18)24)19(20,21)22;5-3(6)1-2-4(7)8/h4-10,13H,11-12H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

HIDE SMILES / InChI

Molecular Formula	C4H4O4
Molecular Weight	116.0722
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Molecular Formula	C19H21F3N2S
Molecular Weight	366.444
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://books.google.ru/books?id=0vXTBwAAQBAJ&pg=PA1236&lpg=PA1236&dq=Nortran retrieved from Dictionary of drugs: Chemical data, structures and bibliographies, edited by J. Elks, p.1236
Curator's Comment: Description was created based on several sources, including https://myhealthbox.eu/en_us/drug/nortrantablets/2391535

Trifluomeprazine is a sedative and hypnotic, it was used in veterinary medicine under the brand name Nortran. Withdrawn from the market.

CNS Activity

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Anxiety 275 Sources: https://cdn.loc.gov/service/ll/fedreg/fr054/fr054008/fr054008.pdf	Primary		Approved 8583	NORTRAN TABLETS Approved Use Nortran (trifluomeprazine) Tablets were intended for use in dogs for tranquilization Launch Date 1972

PubMed

Title	Date	PubMed
Standardised thin-layer chromatographic systems for the identification of drugs and poisons.	1982-10	6758633

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 20:23:06 GMT 2025` Edited by `admin` on `Mon Mar 31 20:23:06 GMT 2025`
Record UNII	YF6LF27282
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TRIFLUOMEPRAZINE MALEATE

Common Name

English

TRIFLUOMEPRAZINE MALEATE [GREEN BOOK]

Preferred Name

English

TRIFLUOMEPRAZINE MALEATE [MART.]

Common Name

English

10H-PHENOTHIAZINE-10-PROPANAMINE, N,N,.BETA.-TRIMETHYL-2-(TRIFLUOROMETHYL)-, 2-BUTENEDIOATE (1:1)

Systematic Name

English

TRIFLUOMEPRAZINE MALEATE [MI]

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID2046886