TRIFLUOMEPRAZINE HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H21F3N2S.ClH
Molecular Weight	402.905
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TRIFLUOMEPRAZINE HYDROCHLORIDE

Structure Search

SMILES

Cl.CC(CN(C)C)CN1C2=CC(=CC=C2SC3=C1C=CC=C3)C(F)(F)F

InChI

InChIKey=JISXJZIKROIEPI-UHFFFAOYSA-N

InChI=1S/C19H21F3N2S.ClH/c1-13(11-23(2)3)12-24-15-6-4-5-7-17(15)25-18-9-8-14(10-16(18)24)19(20,21)22;/h4-10,13H,11-12H2,1-3H3;1H

HIDE SMILES / InChI

Molecular Formula	C19H21F3N2S
Molecular Weight	366.444
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://books.google.ru/books?id=0vXTBwAAQBAJ&pg=PA1236&lpg=PA1236&dq=Nortran retrieved from Dictionary of drugs: Chemical data, structures and bibliographies, edited by J. Elks, p.1236
Curator's Comment: Description was created based on several sources, including https://myhealthbox.eu/en_us/drug/nortrantablets/2391535

Trifluomeprazine is a sedative and hypnotic, it was used in veterinary medicine under the brand name Nortran. Withdrawn from the market.

CNS Activity

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Anxiety 275 Sources: https://cdn.loc.gov/service/ll/fedreg/fr054/fr054008/fr054008.pdf	Primary		Approved 8583	NORTRAN TABLETS Approved Use Nortran (trifluomeprazine) Tablets were intended for use in dogs for tranquilization Launch Date 1972

PubMed

Title	Date	PubMed
Standardised thin-layer chromatographic systems for the identification of drugs and poisons.	1982-10	6758633

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:15:37 GMT 2025` Edited by `admin` on `Mon Mar 31 23:15:37 GMT 2025`
Record UNII	8Y2Y0RG3FV
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TRIFLUOMEPRAZINE HYDROCHLORIDE

Common Name

English

PHENOTHIAZINE, 10-(3-(DIMETHYLAMINO)-2-METHYLPROPYL)-2-(TRIFLUOROMETHYL)-, MONOHYDROCHLORIDE

Preferred Name

English

NSC-156243

Code

English

10H-PHENOTHIAZINE-10-PROPANAMINE, N,N,.BETA.-TRIMETHYL-2-(TRIFLUOROMETHYL)-, HYDROCHLORIDE (1:1)

Systematic Name

English

Code System Code Type Description

FDA UNII

8Y2Y0RG3FV

Created by admin on Mon Mar 31 23:15:37 GMT 2025 , Edited by admin on Mon Mar 31 23:15:37 GMT 2025

PRIMARY

NSC

156243

Created by admin on Mon Mar 31 23:15:37 GMT 2025 , Edited by admin on Mon Mar 31 23:15:37 GMT 2025

PRIMARY

CAS

3800-98-4

Created by admin on Mon Mar 31 23:15:37 GMT 2025 , Edited by admin on Mon Mar 31 23:15:37 GMT 2025

PRIMARY

PUBCHEM

21115103

Created by admin on Mon Mar 31 23:15:37 GMT 2025 , Edited by admin on Mon Mar 31 23:15:37 GMT 2025

PRIMARY

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TRIFLUOMEPRAZINE HYDROCHLORIDE, (R)-

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					A09UYG6TXN

TRIFLUOMEPRAZINE HYDROCHLORIDE, (S)-

ENANTIOMER -> RACEMATE

Details

SMILES

InChI

CNS Activity

Originator

Approval Year

Conditions

Approved Use

Launch Date

PubMed

Patents

Sample Use Guides