Approval Year
| Substance Class |
Nucleic Acid
Created
by
admin
on
Edited
Sat Dec 16 16:55:54 GMT 2023
by
admin
on
Sat Dec 16 16:55:54 GMT 2023
|
| Nucleic Acid Type | RNAI |
| Nucleic Acid Subtype | ANTI-SENSE |
| Sequence Type | COMPLETE |
| Record UNII |
NZL8REY4K6
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Code | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Code | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
EU-Orphan Drug |
EU/3/19/2171
Created by
admin on Sat Dec 16 16:55:54 GMT 2023 , Edited by admin on Sat Dec 16 16:55:54 GMT 2023
|
||
|
FDA ORPHAN DRUG |
702819
Created by
admin on Sat Dec 16 16:55:54 GMT 2023 , Edited by admin on Sat Dec 16 16:55:54 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
NZL8REY4K6
Created by
admin on Sat Dec 16 16:55:54 GMT 2023 , Edited by admin on Sat Dec 16 16:55:54 GMT 2023
|
PRIMARY |
| Sugar | Site Range | Site Count |
|---|---|---|
| Deoxyribose (DNA) | 1_4-1_13 | 10 / 16 |
| 1_1-1_3;1_14-1_16 | 6 / 16 |
| Linkage | Site Range | Site Count |
|---|---|---|
| Sodium Phosporothioate | 1_2-1_16 | 15 / 15 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ACTIVE MOIETY |
|
Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| NUCLEOSIDE BASE SUBSTITUTION | [1_2] [1_3] [1_15] [1_16] | SITE_SPECIFIC | THYMINE | QR26YLT7LT | ||
| NUCLEOSIDE BASE SUBSTITUTION | [1_14] | SITE_SPECIFIC | 5-METHYLCYTOSINE | 6R795CQT4H |