U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Nucleic Acid
Created
by admin
on Wed Apr 02 09:01:06 GMT 2025
Edited
by admin
on Wed Apr 02 09:01:06 GMT 2025
Nucleic Acid Type OLIGONUCLEOTIDE
Sequence Type COMPLETE
Record UNII
6470267545
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DYNAMIN 101 FREE ACID
Preferred Name English
DYN-101 FREE ACID
Code English
IONIS-DNM2-2.5RX FREE ACID
Common Name English
DYNAMIN-101 FREE ACID
Code English
Code System Code Type Description
FDA UNII
6470267545
Created by admin on Wed Apr 02 09:01:06 GMT 2025 , Edited by admin on Wed Apr 02 09:01:06 GMT 2025
PRIMARY
Sugar Site Range Site Count
1_1-1_3;1_14-1_16 6 / 16
Deoxyribose (DNA) 1_4-1_13 10 / 16
Linkage Site Range Site Count
Phosporothioate 1_2-1_16 15 / 15
Related Record Type Details
TARGET->INHIBITOR OF EXPRESSION
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
NUCLEOSIDE BASE SUBSTITUTION [1_14] SITE_SPECIFIC 5-METHYLCYTOSINE 6R795CQT4H
NUCLEOSIDE BASE SUBSTITUTION [1_2] [1_3] [1_15] [1_16] SITE_SPECIFIC THYMINE QR26YLT7LT