Details
Stereochemistry | ACHIRAL |
Molecular Formula | C5H6N2O2 |
Molecular Weight | 126.1135 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cc1cnc(nc1O)O
InChI
InChIKey=RWQNBRDOKXIBIV-UHFFFAOYSA-N
InChI=1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)
Molecular Formula | C5H6N2O2 |
Molecular Weight | 126.1135 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Utilization of amino acids in growing kidney proximal tubule cell cultures. | 2001 |
|
A novel nonsense mutation of the GTP cyclohydrolase I gene in a family with dopa-responsive dystonia. | 2001 |
|
Thymine-metal ion interactions: relevance for thymine quartet structures. | 2001 Apr |
|
Genotyping the -521C/T functional polymorphism in the promoter region of dopamine D4 receptor (DRD4) gene. | 2001 Apr |
|
Mass spectrometric evidence for mechanisms of fragmentation of charge-derivatized peptides. | 2001 Apr |
|
Inheritance of a stable mutation in a family with early-onset disease. | 2001 Apr |
|
Association study of CAG repeats in the KCNN3 gene in Japanese patients with schizophrenia, schizoaffective disorder and bipolar disorder. | 2001 Apr 15 |
|
The crystal structures of psoralen cross-linked DNAs: drug-dependent formation of Holliday junctions. | 2001 Apr 20 |
|
Superoxide dismutases enhance H2O2-induced DNA damage and alter its site specificity. | 2001 Apr 27 |
|
15-mer DNA duplexes containing an abasic site are thermodynamically more stable with adjacent purines than with pyrimidines. | 2001 Apr 3 |
|
N(1)-C(5')-linked dimer hydrates of 5-substituted uracils produced by anodic oxidation in aqueous solution. | 2001 Apr 6 |
|
Biochemical characterization of uracil processing activities in the hyperthermophilic archaeon Pyrobaculum aerophilum. | 2001 Aug 10 |
|
The eosinophil peroxidase-hydrogen peroxide-bromide system of human eosinophils generates 5-bromouracil, a mutagenic thymine analogue. | 2001 Feb 20 |
|
Individual determination of the yield of the main UV-induced dimeric pyrimidine photoproducts in DNA suggests a high mutagenicity of CC photolesions. | 2001 Feb 27 |
|
Synthesis of 1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-substituted-benzenes: "thymine replacement" analogs of thymidine for evaluation as anticancer and antiviral agents. | 2001 Jan-Feb |
|
Exploring the role of the 5'-position of TSAO-T. Synthesis and anti-HIV evaluation of novel TSAO-T derivatives. | 2001 Jun |
|
Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization. | 2001 Jun |
|
Crystal structures of a ddATP-, ddTTP-, ddCTP, and ddGTP- trapped ternary complex of Klentaq1: insights into nucleotide incorporation and selectivity. | 2001 Jun |
|
Monoclonal antibody to single-stranded DNA: a potential tool for DNA repair studies. | 2001 Jun 1 |
|
Stimulation of human endonuclease III by Y box-binding protein 1 (DNA-binding protein B). Interaction between a base excision repair enzyme and a transcription factor. | 2001 Jun 15 |
|
A stem-loop of Tetrahymena telomerase RNA distant from the template potentiates RNA folding and telomerase activity. | 2001 Jun 19 |
|
Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma. | 2001 Jun 29 |
|
Base sequence dependence of in vitro translesional DNA replication past a bulky lesion catalyzed by the exo- Klenow fragment of Pol I. | 2001 Jun 5 |
|
Probing catalysis by Escherichia coli dTDP-glucose-4,6-dehydratase: identification and preliminary characterization of functional amino acid residues at the active site. | 2001 Jun 5 |
|
Role of the Escherichia coli and human DNA glycosylases that remove 5-formyluracil from DNA in the prevention of mutations. | 2001 Mar |
|
The production and evaluation of antibodies for enzyme immunoassay of AZTTP. | 2001 Mar |
|
Low-dose, sublingual AZT-monophosphate therapy for HIV+ patients? | 2001 Mar |
|
Rapid detection of a common dihydropyrimidine dehydrogenase mutation associated with 5-fluorouracil toxicity and congenital thymine uraciluria using fluorogenic hybridization probes. | 2001 Mar |
|
The significance of dihydropyrimidine dehydrogenase (DPD) activity in bladder cancer. | 2001 Mar |
|
p53 effects both the duration of G2/M arrest and the fate of temozolomide-treated human glioblastoma cells. | 2001 Mar 1 |
|
Design and characterization of asparagine- and lysine-containing alanine-based helical peptides that bind selectively to A.T base pairs of oligonucleotides immobilized on a 27 mhz quartz crystal microbalance. | 2001 Mar 27 |
|
Myotonic dystrophy protein kinase (DMPK) gene expression in lymphocytes of patients with myotonic dystrophy. | 2001 Mar-Apr |
|
Construction of peptide conjugates with peptide nucleic acids containing an anthracene probe and their interactions with DNA. | 2001 May |
|
Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency. | 2001 May |
|
Fragmentation mechanisms of oligodeoxynucleotides: effects of replacing phosphates with methylphosphonates and thymines with other bases in T-rich sequences. | 2001 May |
|
Microuli, a family of miniature subterminal inverted-repeat transposable elements (MSITEs): transposition without terminal inverted repeats. | 2001 May |
|
Numerous gene rearrangements in the mitochondrial genome of the wallaby louse, Heterodoxus macropus (Phthiraptera). | 2001 May |
|
Role of spinal alpha1-adrenoceptor subtypes in the bladder reflex in anesthetized rats. | 2001 May |
|
Oxidative DNA damage induced by a metabolite of carcinogenic o-anisidine: enhancement of DNA damage and alteration in its sequence specificity by superoxide dismutase. | 2001 May 1 |
|
An integrated system to study multiply substituted human immunodeficiency virus type 1 reverse transcriptase. | 2001 May 1 |
|
Actinomycin D binds strongly to d(TGTCATTG), a single-stranded DNA devoid of GpC sites. | 2001 May 1 |
|
Oxidation of thymine to 5-formyluracil in DNA promotes misincorporation of dGMP and subsequent elongation of a mismatched primer terminus by DNA polymerase. | 2001 May 11 |
|
Recognition and kinetics for excision of a base lesion within clustered DNA damage by the Escherichia coli proteins Fpg and Nth. | 2001 May 15 |
|
Backbone modifications of aromatic peptide nucleic acid (APNA ) monomers and their hybridization properties with DNA and RNA. | 2001 May 18 |
|
DNA repair mechanism by photolyase: electron transfer path from the photolyase catalytic cofactor FADH(-) to DNA thymine dimer. | 2001 May 21 |
|
Ether phospholipid-AZT conjugates possessing anti-HIV and antitumor cell activity. Synthesis, conformational analysis, and study of their thermal effects on membrane bilayers. | 2001 May 24 |
|
Aminoethylprolyl (aep) PNA: mixed purine/pyrimidine oligomers and binding orientation preferences for PNA:DNA duplex formation. | 2001 May 3 |
|
Pyrrolidine nucleic acids: DNA/PNA oligomers with 2-hydroxy/aminomethyl- 4-(thymin-1-yl)pyrrolidine-N-acetic acid. | 2001 May 3 |
|
Insight into the catalytic mechanism of DNA polymerase beta: structures of intermediate complexes. | 2001 May 8 |
|
Mutations induced by 5-formyl-2'-deoxyuridine in Escherichia coli include base substitutions that can arise from mispairs of 5-formyluracil with guanine, cytosine and thymine. | 2001 May 9 |
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Jun 26 03:46:20 UTC 2021
by
admin
on
Sat Jun 26 03:46:20 UTC 2021
|
Record UNII |
QR26YLT7LT
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
---|---|---|---|---|
|
Official Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Systematic Name | English |
Classification Tree | Code System | Code | ||
---|---|---|---|---|
|
LOINC |
48157-2
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
||
|
LOINC |
75153-7
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
||
|
LOINC |
75121-4
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
||
|
NCI_THESAURUS |
C789
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
QR26YLT7LT
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
PRIMARY | |||
|
M10823
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
PRIMARY | Merck Index | ||
|
1135
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
PRIMARY | |||
|
65-71-4
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
PRIMARY | |||
|
D013941
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
PRIMARY | |||
|
200-616-1
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
PRIMARY | |||
|
1724532
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
PRIMARY | USP-RS | ||
|
DB03462
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
PRIMARY | |||
|
C881
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
PRIMARY | |||
|
65-71-4
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
PRIMARY | |||
|
THYMINE
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
PRIMARY | |||
|
1368871
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
PRIMARY | RxNorm | ||
|
SUB27112
Created by
admin on Sat Jun 26 03:46:20 UTC 2021 , Edited by admin on Sat Jun 26 03:46:20 UTC 2021
|
PRIMARY |
Related Record | Type | Details | ||
---|---|---|---|---|
|
METABOLITE -> PARENT |
BAIBA induces energy expenditure in adipocytes and distal fat tissues, and ?-oxidation of hepatic fatty acids in part via activation of peroxisome proliferators-activated receptor ? (PPAR?) [33]. Notably, in humans, plasma BAIBA concentrations increase with exercise and are inversely associated with metabolic risk factors.
|
||
|
PARENT -> METABOLITE |
Related Record | Type | Details | ||
---|---|---|---|---|
|
PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
|
||
|
PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
|
||
|
PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
|
||
|
PARENT -> IMPURITY |
Amount Not Specified
INTERNATIONAL PHARMACOPEIA
|
||
|
PARENT -> IMPURITY |
Calculation of percentage contents: – correction factor: multiply the peak area of impurity A by 0.7
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
|
Related Record | Type | Details | ||
---|---|---|---|---|
|
ACTIVE MOIETY |