U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C5H6N2O2
Molecular Weight 126.1133
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of THYMINE

SMILES

CC1=CNC(=O)NC1=O

InChI

InChIKey=RWQNBRDOKXIBIV-UHFFFAOYSA-N
InChI=1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)

HIDE SMILES / InChI

Molecular Formula C5H6N2O2
Molecular Weight 126.1133
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Defects in pyrimidine degradation identified by HPLC-electrospray tandem mass spectrometry of urine specimens or urine-soaked filter paper strips.
2000 Dec
Adenine-induced selective apoptosis toward HIV chronically infected cells in vitro.
2000 Jul 14
A novel nonsense mutation of the GTP cyclohydrolase I gene in a family with dopa-responsive dystonia.
2001
A novel polymorphism IVS2+843C>T in the alternate promoter b1 of the human AE2 anion exchanger gene.
2001
Phylogeny, function, and evolution of the cupins, a structurally conserved, functionally diverse superfamily of proteins.
2001 Apr
Low-energy (5-40 eV) electron-stimulated desorption of anions from physisorbed DNA bases.
2001 Apr
Binding of nucleotides to nucleoside diphosphate kinase: a calorimetric study.
2001 Apr 17
The crystal structures of psoralen cross-linked DNAs: drug-dependent formation of Holliday junctions.
2001 Apr 20
Superoxide dismutases enhance H2O2-induced DNA damage and alter its site specificity.
2001 Apr 27
N(1)-C(5')-linked dimer hydrates of 5-substituted uracils produced by anodic oxidation in aqueous solution.
2001 Apr 6
Biochemical characterization of uracil processing activities in the hyperthermophilic archaeon Pyrobaculum aerophilum.
2001 Aug 10
Characterization of DNA damage at purine residues in oligonucleotides and calf thymus DNA induced by the mutagen 1-nitrosoindole-3-acetonitrile.
2001 Feb
Induction and excretion of ultraviolet-induced 8-oxo-2'-deoxyguanosine and thymine dimers in vivo: implications for PUVA.
2001 Feb
Stimulation of melanogenesis by DNA oligonucleotides: effect of size, sequence and 5' phosphorylation.
2001 Feb
Molecular diversity of quinolone resistance in genetically related clinical isolates of Staphylococcus aureus and susceptibility to newer quinolones.
2001 Feb
Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti-cancer drug 5-fluorouracil.
2001 Feb 15
Determination of high-energy phosphate compounds and inorganic phosphate by reversed-phase high-performance liquid chromatography: evaluation of myocardial metabolic status in aerobically perfused and hypoxic mouse heart.
2001 Feb 25
5-Formyluracil and its nucleoside derivatives confer toxicity and mutagenicity to mammalian cells by interfering with normal RNA and DNA metabolism.
2001 Feb 3
An electrochemical evidence of free radicals formation from flutamide and its reactivity with endo/xenobiotics of pharmacological relevance.
2001 Jan
The transport of a reversible proton pump antagonist, 5, 6-dimethyl-2-(4-Fluorophenylamino)-4-(1-methyl-1,2,3, 4-tetrahydroisoquinoline-2-yl) pyrimidine hydrochloride (YH1885), across caco-2 cell monolayers.
2001 Jan
Exploring the role of the 5'-position of TSAO-T. Synthesis and anti-HIV evaluation of novel TSAO-T derivatives.
2001 Jun
Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma.
2001 Jun 29
Low-dose, sublingual AZT-monophosphate therapy for HIV+ patients?
2001 Mar
Rapid detection of a common dihydropyrimidine dehydrogenase mutation associated with 5-fluorouracil toxicity and congenital thymine uraciluria using fluorogenic hybridization probes.
2001 Mar
p53 effects both the duration of G2/M arrest and the fate of temozolomide-treated human glioblastoma cells.
2001 Mar 1
Solution structure of an A-tract DNA bend.
2001 Mar 9
Microuli, a family of miniature subterminal inverted-repeat transposable elements (MSITEs): transposition without terminal inverted repeats.
2001 May
Role of MED1 (MBD4) Gene in DNA repair and human cancer.
2001 May
Catechol estrogens induce oxidative DNA damage and estradiol enhances cell proliferation.
2001 May 1
Oxidation of thymine to 5-formyluracil in DNA promotes misincorporation of dGMP and subsequent elongation of a mismatched primer terminus by DNA polymerase.
2001 May 11
DNA repair mechanism by photolyase: electron transfer path from the photolyase catalytic cofactor FADH(-) to DNA thymine dimer.
2001 May 21
Aminoethylprolyl (aep) PNA: mixed purine/pyrimidine oligomers and binding orientation preferences for PNA:DNA duplex formation.
2001 May 3
Pyrrolidine nucleic acids: DNA/PNA oligomers with 2-hydroxy/aminomethyl- 4-(thymin-1-yl)pyrrolidine-N-acetic acid.
2001 May 3
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:00:18 UTC 2023
Edited
by admin
on Fri Dec 15 15:00:18 UTC 2023
Record UNII
QR26YLT7LT
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
THYMINE
INCI   MI   WHO-DD  
INCI  
Official Name English
5-METHYL URACIL
Systematic Name English
ZIDOVUDINE RELATED COMPOUND C
USP-RS  
Common Name English
THYMINE [USP IMPURITY]
Common Name English
Thymine [WHO-DD]
Common Name English
STAVUINE IMPURITY A [WHO-IP]
Common Name English
THYMINE [INCI]
Common Name English
ZIDOVUDINE RELATED COMPOUND C [USP-RS]
Common Name English
THYMIN
Systematic Name English
ZIDOVUDINE IMPURITY C [WHO-IP]
Common Name English
ZIDOVUDINE IMPURITY C [EP IMPURITY]
Common Name English
ZIDOVUDINE RELATED COMPOUND C [USP IMPURITY]
Common Name English
NSC-168663
Code English
5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE (THYMINE)
Common Name English
NSC-14705
Code English
THYMINE [MI]
Common Name English
5-METHYL-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE
Systematic Name English
Classification Tree Code System Code
LOINC 48157-2
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
LOINC 75153-7
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
LOINC 75121-4
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
NCI_THESAURUS C789
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
Code System Code Type Description
FDA UNII
QR26YLT7LT
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY
MERCK INDEX
m10823
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY Merck Index
PUBCHEM
1135
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY
CAS
65-71-4
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY
NSC
168663
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY
MESH
D013941
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-616-1
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY
SMS_ID
100000091723
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY
DRUG BANK
DB03462
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY
NCI_THESAURUS
C881
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY
RS_ITEM_NUM
1724532
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY
DAILYMED
QR26YLT7LT
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY
CHEBI
17821
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY
EPA CompTox
DTXSID4052342
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY
WIKIPEDIA
THYMINE
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY
RXCUI
1368871
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY RxNorm
NSC
14705
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY
EVMPD
SUB27112
Created by admin on Fri Dec 15 15:00:18 UTC 2023 , Edited by admin on Fri Dec 15 15:00:18 UTC 2023
PRIMARY
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