U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C5H6N2O2
Molecular Weight 126.1133
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of THYMINE

SMILES

CC1=CNC(=O)NC1=O

InChI

InChIKey=RWQNBRDOKXIBIV-UHFFFAOYSA-N
InChI=1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)

HIDE SMILES / InChI

Molecular Formula C5H6N2O2
Molecular Weight 126.1133
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Adenine-induced selective apoptosis toward HIV chronically infected cells in vitro.
2000 Jul 14
Utilization of amino acids in growing kidney proximal tubule cell cultures.
2001
Mechanisms of nitric oxide-induced cytotoxicity in normal human hepatocytes.
2001
A novel polymorphism IVS2+843C>T in the alternate promoter b1 of the human AE2 anion exchanger gene.
2001
Ionization mechanism of oligonucleotides in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
2001
Thymine-metal ion interactions: relevance for thymine quartet structures.
2001 Apr
Phylogeny, function, and evolution of the cupins, a structurally conserved, functionally diverse superfamily of proteins.
2001 Apr
Binding of nucleotides to nucleoside diphosphate kinase: a calorimetric study.
2001 Apr 17
15-mer DNA duplexes containing an abasic site are thermodynamically more stable with adjacent purines than with pyrimidines.
2001 Apr 3
Characterization of DNA damage at purine residues in oligonucleotides and calf thymus DNA induced by the mutagen 1-nitrosoindole-3-acetonitrile.
2001 Feb
Confounded cytosine! Tinkering and the evolution of DNA.
2001 Feb
Haplotype analyses with the human leucocyte antigen and tumour necrosis factor-alpha genes in narcolepsy families.
2001 Feb
Metastable decay of negatively charged oligodeoxynucleotides analyzed with ultraviolet matrix-assisted laser desorption/ionization post-source decay and deuterium exchange.
2001 Feb
Enhanced S phase delay and inhibition of replication of an undamaged shuttle vector in UVC-irradiated xeroderma pigmentosum variant.
2001 Feb
The eosinophil peroxidase-hydrogen peroxide-bromide system of human eosinophils generates 5-bromouracil, a mutagenic thymine analogue.
2001 Feb 20
Determination of high-energy phosphate compounds and inorganic phosphate by reversed-phase high-performance liquid chromatography: evaluation of myocardial metabolic status in aerobically perfused and hypoxic mouse heart.
2001 Feb 25
Individual determination of the yield of the main UV-induced dimeric pyrimidine photoproducts in DNA suggests a high mutagenicity of CC photolesions.
2001 Feb 27
Enhanced loop DNA folding induced by thymine-CH3 group contact and perpendicular guanine-thymine interaction.
2001 Jan
Mutagenic effects of 5-formyluracil on a plasmid vector during replication in Escherichia coli.
2001 Jan
An electrochemical evidence of free radicals formation from flutamide and its reactivity with endo/xenobiotics of pharmacological relevance.
2001 Jan
MNGIE: from nuclear DNA to mitochondrial DNA.
2001 Jan
A study of peptide--peptide interaction by matrix-assisted laser desorption/ionization.
2001 Jan
The transport of a reversible proton pump antagonist, 5, 6-dimethyl-2-(4-Fluorophenylamino)-4-(1-methyl-1,2,3, 4-tetrahydroisoquinoline-2-yl) pyrimidine hydrochloride (YH1885), across caco-2 cell monolayers.
2001 Jan
Interferon gamma-dependent induction of thymidine phosphorylase/platelet-derived endothelial growth factor through gamma-activated sequence-like element in human macrophages.
2001 Jan 15
Minor groove functional groups are critical for the B-form conformation of duplex DNA.
2001 Jan 30
Conformation and dynamics of abasic sites in DNA investigated by time-resolved fluorescence of 2-aminopurine.
2001 Jan 30
Synthesis of 1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-substituted-benzenes: "thymine replacement" analogs of thymidine for evaluation as anticancer and antiviral agents.
2001 Jan-Feb
Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization.
2001 Jun
Stimulation of human endonuclease III by Y box-binding protein 1 (DNA-binding protein B). Interaction between a base excision repair enzyme and a transcription factor.
2001 Jun 15
A stem-loop of Tetrahymena telomerase RNA distant from the template potentiates RNA folding and telomerase activity.
2001 Jun 19
Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma.
2001 Jun 29
The production and evaluation of antibodies for enzyme immunoassay of AZTTP.
2001 Mar
The significance of dihydropyrimidine dehydrogenase (DPD) activity in bladder cancer.
2001 Mar
A seminested PCR test for simultaneous detection of two common mutations (35delG and 167delT) in the connexin-26 gene.
2001 Mar
No detectable DNA excision repair in UV-exposed hepatocytes from two catfish species.
2001 Mar
Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke.
2001 Mar
Affinity of mismatch-binding protein MutS for heteroduplexes containing different mismatches.
2001 Mar 15
The crystal structure of dTDP-D-Glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar Typhimurium, the second enzyme in the dTDP-l-rhamnose pathway.
2001 Mar 16
Design and characterization of asparagine- and lysine-containing alanine-based helical peptides that bind selectively to A.T base pairs of oligonucleotides immobilized on a 27 mhz quartz crystal microbalance.
2001 Mar 27
Solution structure of an A-tract DNA bend.
2001 Mar 9
Myotonic dystrophy protein kinase (DMPK) gene expression in lymphocytes of patients with myotonic dystrophy.
2001 Mar-Apr
Fragmentation mechanisms of oligodeoxynucleotides: effects of replacing phosphates with methylphosphonates and thymines with other bases in T-rich sequences.
2001 May
Microuli, a family of miniature subterminal inverted-repeat transposable elements (MSITEs): transposition without terminal inverted repeats.
2001 May
Numerous gene rearrangements in the mitochondrial genome of the wallaby louse, Heterodoxus macropus (Phthiraptera).
2001 May
Role of spinal alpha1-adrenoceptor subtypes in the bladder reflex in anesthetized rats.
2001 May
Oxidative DNA damage induced by a metabolite of carcinogenic o-anisidine: enhancement of DNA damage and alteration in its sequence specificity by superoxide dismutase.
2001 May 1
An integrated system to study multiply substituted human immunodeficiency virus type 1 reverse transcriptase.
2001 May 1
Ether phospholipid-AZT conjugates possessing anti-HIV and antitumor cell activity. Synthesis, conformational analysis, and study of their thermal effects on membrane bilayers.
2001 May 24
Aminoethylprolyl (aep) PNA: mixed purine/pyrimidine oligomers and binding orientation preferences for PNA:DNA duplex formation.
2001 May 3
Mutations induced by 5-formyl-2'-deoxyuridine in Escherichia coli include base substitutions that can arise from mispairs of 5-formyluracil with guanine, cytosine and thymine.
2001 May 9
Patents
Substance Class Chemical
Created
by admin
on Wed Jul 05 22:32:21 UTC 2023
Edited
by admin
on Wed Jul 05 22:32:21 UTC 2023
Record UNII
QR26YLT7LT
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
THYMINE
INCI   MI   WHO-DD  
INCI  
Official Name English
5-METHYL URACIL
Systematic Name English
ZIDOVUDINE RELATED COMPOUND C
USP-RS  
Common Name English
THYMINE [USP IMPURITY]
Common Name English
Thymine [WHO-DD]
Common Name English
STAVUINE IMPURITY A [WHO-IP]
Common Name English
THYMINE [INCI]
Common Name English
ZIDOVUDINE RELATED COMPOUND C [USP-RS]
Common Name English
THYMIN
Systematic Name English
ZIDOVUDINE IMPURITY C [WHO-IP]
Common Name English
ZIDOVUDINE IMPURITY C [EP IMPURITY]
Common Name English
ZIDOVUDINE RELATED COMPOUND C [USP IMPURITY]
Common Name English
NSC-168663
Code English
5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE (THYMINE)
Common Name English
NSC-14705
Code English
THYMINE [MI]
Common Name English
5-METHYL-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE
Systematic Name English
Classification Tree Code System Code
LOINC 48157-2
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
LOINC 75153-7
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
LOINC 75121-4
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
NCI_THESAURUS C789
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
Code System Code Type Description
FDA UNII
QR26YLT7LT
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
PRIMARY
MERCK INDEX
M10823
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
PRIMARY Merck Index
PUBCHEM
1135
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
PRIMARY
CAS
65-71-4
Created by admin on Wed Jul 05 22:32:21 UTC 2023 , Edited by admin on Wed Jul 05 22:32:21 UTC 2023
PRIMARY
NSC
168663
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
PRIMARY
MESH
D013941
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-616-1
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
PRIMARY
SMS_ID
100000091723
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
PRIMARY
DRUG BANK
DB03462
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
PRIMARY
NCI_THESAURUS
C881
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
PRIMARY
RS_ITEM_NUM
1724532
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
PRIMARY
DAILYMED
QR26YLT7LT
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
PRIMARY
CHEBI
17821
Created by admin on Wed Jul 05 22:32:21 UTC 2023 , Edited by admin on Wed Jul 05 22:32:21 UTC 2023
PRIMARY
EPA CompTox
DTXSID4052342
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
PRIMARY
WIKIPEDIA
THYMINE
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
PRIMARY
RXCUI
1368871
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
PRIMARY RxNorm
NSC
14705
Created by admin on Wed Jul 05 22:32:22 UTC 2023 , Edited by admin on Wed Jul 05 22:32:22 UTC 2023
PRIMARY
EVMPD
SUB27112
Created by admin on Wed Jul 05 22:32:21 UTC 2023 , Edited by admin on Wed Jul 05 22:32:21 UTC 2023
PRIMARY
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