Details
Stereochemistry | ACHIRAL |
Molecular Formula | C5H6N2O2 |
Molecular Weight | 126.1133 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CNC(=O)NC1=O
InChI
InChIKey=RWQNBRDOKXIBIV-UHFFFAOYSA-N
InChI=1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)
Molecular Formula | C5H6N2O2 |
Molecular Weight | 126.1133 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
PubMed
Title | Date | PubMed |
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Adenine-induced selective apoptosis toward HIV chronically infected cells in vitro. | 2000 Jul 14 |
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Utilization of amino acids in growing kidney proximal tubule cell cultures. | 2001 |
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Mechanisms of nitric oxide-induced cytotoxicity in normal human hepatocytes. | 2001 |
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A novel polymorphism IVS2+843C>T in the alternate promoter b1 of the human AE2 anion exchanger gene. | 2001 |
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Ionization mechanism of oligonucleotides in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. | 2001 |
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Thymine-metal ion interactions: relevance for thymine quartet structures. | 2001 Apr |
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Phylogeny, function, and evolution of the cupins, a structurally conserved, functionally diverse superfamily of proteins. | 2001 Apr |
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Binding of nucleotides to nucleoside diphosphate kinase: a calorimetric study. | 2001 Apr 17 |
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15-mer DNA duplexes containing an abasic site are thermodynamically more stable with adjacent purines than with pyrimidines. | 2001 Apr 3 |
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Characterization of DNA damage at purine residues in oligonucleotides and calf thymus DNA induced by the mutagen 1-nitrosoindole-3-acetonitrile. | 2001 Feb |
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Confounded cytosine! Tinkering and the evolution of DNA. | 2001 Feb |
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Haplotype analyses with the human leucocyte antigen and tumour necrosis factor-alpha genes in narcolepsy families. | 2001 Feb |
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Metastable decay of negatively charged oligodeoxynucleotides analyzed with ultraviolet matrix-assisted laser desorption/ionization post-source decay and deuterium exchange. | 2001 Feb |
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Enhanced S phase delay and inhibition of replication of an undamaged shuttle vector in UVC-irradiated xeroderma pigmentosum variant. | 2001 Feb |
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The eosinophil peroxidase-hydrogen peroxide-bromide system of human eosinophils generates 5-bromouracil, a mutagenic thymine analogue. | 2001 Feb 20 |
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Determination of high-energy phosphate compounds and inorganic phosphate by reversed-phase high-performance liquid chromatography: evaluation of myocardial metabolic status in aerobically perfused and hypoxic mouse heart. | 2001 Feb 25 |
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Individual determination of the yield of the main UV-induced dimeric pyrimidine photoproducts in DNA suggests a high mutagenicity of CC photolesions. | 2001 Feb 27 |
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Enhanced loop DNA folding induced by thymine-CH3 group contact and perpendicular guanine-thymine interaction. | 2001 Jan |
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Mutagenic effects of 5-formyluracil on a plasmid vector during replication in Escherichia coli. | 2001 Jan |
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An electrochemical evidence of free radicals formation from flutamide and its reactivity with endo/xenobiotics of pharmacological relevance. | 2001 Jan |
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MNGIE: from nuclear DNA to mitochondrial DNA. | 2001 Jan |
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A study of peptide--peptide interaction by matrix-assisted laser desorption/ionization. | 2001 Jan |
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The transport of a reversible proton pump antagonist, 5, 6-dimethyl-2-(4-Fluorophenylamino)-4-(1-methyl-1,2,3, 4-tetrahydroisoquinoline-2-yl) pyrimidine hydrochloride (YH1885), across caco-2 cell monolayers. | 2001 Jan |
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Interferon gamma-dependent induction of thymidine phosphorylase/platelet-derived endothelial growth factor through gamma-activated sequence-like element in human macrophages. | 2001 Jan 15 |
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Minor groove functional groups are critical for the B-form conformation of duplex DNA. | 2001 Jan 30 |
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Conformation and dynamics of abasic sites in DNA investigated by time-resolved fluorescence of 2-aminopurine. | 2001 Jan 30 |
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Synthesis of 1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-substituted-benzenes: "thymine replacement" analogs of thymidine for evaluation as anticancer and antiviral agents. | 2001 Jan-Feb |
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Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization. | 2001 Jun |
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Stimulation of human endonuclease III by Y box-binding protein 1 (DNA-binding protein B). Interaction between a base excision repair enzyme and a transcription factor. | 2001 Jun 15 |
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A stem-loop of Tetrahymena telomerase RNA distant from the template potentiates RNA folding and telomerase activity. | 2001 Jun 19 |
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Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma. | 2001 Jun 29 |
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The production and evaluation of antibodies for enzyme immunoassay of AZTTP. | 2001 Mar |
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The significance of dihydropyrimidine dehydrogenase (DPD) activity in bladder cancer. | 2001 Mar |
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A seminested PCR test for simultaneous detection of two common mutations (35delG and 167delT) in the connexin-26 gene. | 2001 Mar |
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No detectable DNA excision repair in UV-exposed hepatocytes from two catfish species. | 2001 Mar |
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Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke. | 2001 Mar |
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Affinity of mismatch-binding protein MutS for heteroduplexes containing different mismatches. | 2001 Mar 15 |
|
The crystal structure of dTDP-D-Glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar Typhimurium, the second enzyme in the dTDP-l-rhamnose pathway. | 2001 Mar 16 |
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Design and characterization of asparagine- and lysine-containing alanine-based helical peptides that bind selectively to A.T base pairs of oligonucleotides immobilized on a 27 mhz quartz crystal microbalance. | 2001 Mar 27 |
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Solution structure of an A-tract DNA bend. | 2001 Mar 9 |
|
Myotonic dystrophy protein kinase (DMPK) gene expression in lymphocytes of patients with myotonic dystrophy. | 2001 Mar-Apr |
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Fragmentation mechanisms of oligodeoxynucleotides: effects of replacing phosphates with methylphosphonates and thymines with other bases in T-rich sequences. | 2001 May |
|
Microuli, a family of miniature subterminal inverted-repeat transposable elements (MSITEs): transposition without terminal inverted repeats. | 2001 May |
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Numerous gene rearrangements in the mitochondrial genome of the wallaby louse, Heterodoxus macropus (Phthiraptera). | 2001 May |
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Role of spinal alpha1-adrenoceptor subtypes in the bladder reflex in anesthetized rats. | 2001 May |
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Oxidative DNA damage induced by a metabolite of carcinogenic o-anisidine: enhancement of DNA damage and alteration in its sequence specificity by superoxide dismutase. | 2001 May 1 |
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An integrated system to study multiply substituted human immunodeficiency virus type 1 reverse transcriptase. | 2001 May 1 |
|
Ether phospholipid-AZT conjugates possessing anti-HIV and antitumor cell activity. Synthesis, conformational analysis, and study of their thermal effects on membrane bilayers. | 2001 May 24 |
|
Aminoethylprolyl (aep) PNA: mixed purine/pyrimidine oligomers and binding orientation preferences for PNA:DNA duplex formation. | 2001 May 3 |
|
Mutations induced by 5-formyl-2'-deoxyuridine in Escherichia coli include base substitutions that can arise from mispairs of 5-formyluracil with guanine, cytosine and thymine. | 2001 May 9 |
Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Jul 05 22:32:21 UTC 2023
by
admin
on
Wed Jul 05 22:32:21 UTC 2023
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Record UNII |
QR26YLT7LT
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Record Status |
Validated (UNII)
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Record Version |
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LOINC |
48157-2
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LOINC |
75153-7
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LOINC |
75121-4
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NCI_THESAURUS |
C789
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Code System | Code | Type | Description | ||
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QR26YLT7LT
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M10823
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1135
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65-71-4
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168663
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D013941
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200-616-1
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100000091723
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DB03462
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C881
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1724532
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QR26YLT7LT
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17821
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DTXSID4052342
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THYMINE
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1368871
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14705
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SUB27112
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Related Record | Type | Details | ||
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METABOLITE -> PARENT |
BAIBA induces energy expenditure in adipocytes and distal fat tissues, and β-oxidation of hepatic fatty acids in part via activation of peroxisome proliferators-activated receptor α (PPARα) [33]. Notably, in humans, plasma BAIBA concentrations increase with exercise and are inversely associated with metabolic risk factors.
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PARENT -> METABOLITE |
Related Record | Type | Details | ||
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
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PARENT -> IMPURITY |
Amount Not Specified
INTERNATIONAL PHARMACOPEIA
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PARENT -> IMPURITY |
Calculation of percentage contents: – correction factor: multiply the peak area of impurity A by 0.7
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
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Related Record | Type | Details | ||
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ACTIVE MOIETY |