IMAGABALIN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C9H19NO2
Molecular Weight	173.2527
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC[C@@H](C)C[C@H](N)CC(O)=O

InChI

InChIKey=JXEHXYFSIOYTAH-SFYZADRCSA-N

InChI=1S/C9H19NO2/c1-3-4-7(2)5-8(10)6-9(11)12/h7-8H,3-6,10H2,1-2H3,(H,11,12)/t7-,8+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C9H19NO2
Molecular Weight	173.2527
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://clinicaltrials.gov/ct2/show/NCT00738738 | https://www.ncbi.nlm.nih.gov/pubmed/21664606

Imagabalin is a ligand to the α(2)δ subunit of voltage-sensitive calcium channel and was developed to treat generalized anxiety disorder. Imagabalin was involved in phase III clinical trials when was made a decision to terminate all studies. However, this decision was not based on any safety concerns.

Originator

Approval Year

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

Dosage from: 50-100 mg oral capsule Dosage and frequency: 50-350 mg once or twice a day Duration: 6 months

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:02:33 GMT 2023` Edited by `admin` on `Sat Dec 16 17:02:33 GMT 2023`
Record UNII	NDG6931B7H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IMAGABALIN

Official Name

English

OCTANOIC ACID, 3-AMINO-5-METHYL-, (3S,5R)-

Common Name

English

PD-0332334

Code

English

PD0332334

Code

English

(3S,5R)-3-Amino-5-methyl-octanoic acid

Systematic Name

English

imagabalin [INN]

Common Name

English

IMAGABALIN [USAN]

Common Name

English

PF-00195889

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C28197