IMAGABALIN HYDROCHLORIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C9H19NO2.ClH
Molecular Weight	209.714
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CCC[C@@H](C)C[C@H](N)CC(O)=O

InChI

InChIKey=CFMZXQJDAJXNHS-WLYNEOFISA-N

InChI=1S/C9H19NO2.ClH/c1-3-4-7(2)5-8(10)6-9(11)12;/h7-8H,3-6,10H2,1-2H3,(H,11,12);1H/t7-,8+;/m1./s1

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C9H19NO2
Molecular Weight	173.2527
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://clinicaltrials.gov/ct2/show/NCT00738738 | https://www.ncbi.nlm.nih.gov/pubmed/21664606

Imagabalin is a ligand to the α(2)δ subunit of voltage-sensitive calcium channel and was developed to treat generalized anxiety disorder. Imagabalin was involved in phase III clinical trials when was made a decision to terminate all studies. However, this decision was not based on any safety concerns.

Originator

Approval Year

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

Dosage from: 50-100 mg oral capsule Dosage and frequency: 50-350 mg once or twice a day Duration: 6 months

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:09:08 GMT 2023` Edited by `admin` on `Fri Dec 15 16:09:08 GMT 2023`
Record UNII	MJ3F8ZA7Q1
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IMAGABALIN HYDROCHLORIDE

Official Name

English

(3S,5R)-3-Amino-5-methyl-octanoic acid hydrochloride

Systematic Name

English

IMAGABALIN HYDROCHLORIDE [USAN]

Common Name

English

OCTANOIC ACID, 3-AMINO-5-METHYL-, HYDROCHLORIDE, (3S,5R)-

Common Name

English

PD-0332334-0002

Code

English

OCTANOIC ACID, 3-AMINO-5-METHYL-, HYDROCHLORIDE (1:1), (3S,5R)-

Common Name

English

PF00195889-01

Code

English

PF-00195889-01

Code

English

PD 0332334-0002

Code

English

IMAGABALIN HCL

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28197