Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 15:02:26 GMT 2023
by
admin
on
Sat Dec 16 15:02:26 GMT 2023
|
| Protein Type | TRANSPORTER |
| Protein Sub Type | ION CHANNEL |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
Z2CHJ67SHZ
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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Z2CHJ67SHZ
Created by
admin on Sat Dec 16 15:02:27 GMT 2023 , Edited by admin on Sat Dec 16 15:02:27 GMT 2023
|
PRIMARY | |||
|
P54289
Created by
admin on Sat Dec 16 15:02:27 GMT 2023 , Edited by admin on Sat Dec 16 15:02:27 GMT 2023
|
PRIMARY |
| From | To |
|---|---|
| 1_380 | 1_1035 |
| Glycosylation Link Type | Site |
|---|---|
| N | 1_68 |
| N | 1_112 |
| N | 1_160 |
| N | 1_300 |
| N | 1_324 |
| N | 1_444 |
| N | 1_451 |
| N | 1_580 |
| N | 1_589 |
| N | 1_651 |
| N | 1_757 |
| N | 1_800 |
| N | 1_864 |
| N | 1_871 |
| N | 1_961 |
| N | 1_974 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
LIGAND->TARGET |
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LIGAND->TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
PreventS [3H]gabapentin from binding in a dose-dependent manner. Lowers calcium influxupon activation.
IC50
|
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|
INHIBITOR -> TARGET |
ReduceS depolarization-induced calcium influx at nerve terminals, with a consequential reduction in the release of several excitatory neurotransmitters, including glutamate, noradrenaline, substance P, and CGRP.
IC50
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INHIBITOR -> TARGET | |||
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LIGAND->TARGET |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
|