OLICERIDINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H30N2O2S
Molecular Weight	386.551
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of OLICERIDINE

Structure Search

SMILES

COC1=C(CNCC[C@]2(CCOC3(CCCC3)C2)C4=NC=CC=C4)SC=C1

InChI

InChIKey=DMNOVGJWPASQDL-OAQYLSRUSA-N

InChI=1S/C22H30N2O2S/c1-25-18-7-15-27-19(18)16-23-13-10-21(20-6-2-5-12-24-20)11-14-26-22(17-21)8-3-4-9-22/h2,5-7,12,15,23H,3-4,8-11,13-14,16-17H2,1H3/t21-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C22H30N2O2S
Molecular Weight	386.551
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Thu Jul 06 21:32:25 UTC 2023` Edited by `admin` on `Thu Jul 06 21:32:25 UTC 2023`
Record UNII	MCN858TCP0
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

OLICERIDINE

Official Name

English

Oliceridine [WHO-DD]

Common Name

English

TRV130

Code

English

oliceridine [INN]

Common Name

English

TRV-130

Code

English

OLICERIDINE [MI]

Common Name

English

6-OXASPIRO(4.5)DECANE-9-ETHANAMINE, N-((3-METHOXY-2-THIENYL)METHYL)-9-(2-PYRIDINYL)-, (9R)-

Systematic Name

English

OLICERIDINE [ORANGE BOOK]

Common Name

English

OLICERIDINE [USAN]

Common Name

English

N-[(3-Methoxythiophen-2-yl)methyl]-2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]ethanamine

Systematic Name

English

OLINVYK

Brand Name

English

Classification Tree Code System Code

DEA NO.

9245

Created by admin on Thu Jul 06 21:32:26 UTC 2023 , Edited by admin on Thu Jul 06 21:32:26 UTC 2023

Code System Code Type Description

CAS

1401028-24-7

Created by admin on Thu Jul 06 21:32:26 UTC 2023 , Edited by admin on Thu Jul 06 21:32:26 UTC 2023

PRIMARY

DRUG BANK

DB14881

Created by admin on Thu Jul 06 21:32:26 UTC 2023 , Edited by admin on Thu Jul 06 21:32:26 UTC 2023

PRIMARY

INN

10250

Created by admin on Thu Jul 06 21:32:26 UTC 2023 , Edited by admin on Thu Jul 06 21:32:26 UTC 2023

PRIMARY

NCI_THESAURUS

C174704

Created by admin on Thu Jul 06 21:32:26 UTC 2023 , Edited by admin on Thu Jul 06 21:32:26 UTC 2023

PRIMARY

MERCK INDEX

M12219

Created by admin on Thu Jul 06 21:32:26 UTC 2023 , Edited by admin on Thu Jul 06 21:32:26 UTC 2023

PRIMARY

WIKIPEDIA

Oliceridine

Created by admin on Thu Jul 06 21:32:26 UTC 2023 , Edited by admin on Thu Jul 06 21:32:26 UTC 2023

PRIMARY

PUBCHEM

66553195

Created by admin on Thu Jul 06 21:32:26 UTC 2023 , Edited by admin on Thu Jul 06 21:32:26 UTC 2023

PRIMARY

EPA CompTox

DTXSID201031292

Created by admin on Thu Jul 06 21:32:26 UTC 2023 , Edited by admin on Thu Jul 06 21:32:26 UTC 2023

PRIMARY

SMS_ID

300000034256

Created by admin on Thu Jul 06 21:32:26 UTC 2023 , Edited by admin on Thu Jul 06 21:32:26 UTC 2023

PRIMARY

FDA UNII

MCN858TCP0

Created by admin on Thu Jul 06 21:32:26 UTC 2023 , Edited by admin on Thu Jul 06 21:32:26 UTC 2023

PRIMARY

USAN

CD-26

Created by admin on Thu Jul 06 21:32:26 UTC 2023 , Edited by admin on Thu Jul 06 21:32:26 UTC 2023

PRIMARY

RXCUI

2392230

Created by admin on Thu Jul 06 21:32:26 UTC 2023 , Edited by admin on Thu Jul 06 21:32:26 UTC 2023

PRIMARY

ChEMBL

CHEMBL2443262

Created by admin on Thu Jul 06 21:32:26 UTC 2023 , Edited by admin on Thu Jul 06 21:32:26 UTC 2023

PRIMARY

DAILYMED

MCN858TCP0

Created by admin on Thu Jul 06 21:32:26 UTC 2023 , Edited by admin on Thu Jul 06 21:32:26 UTC 2023

PRIMARY

Related Record Type Details


					L9DP834D1P

CYTOCHROME P450 2C9

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MINOR


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					0JE2QYQ7CW

OLICERIDINE FUMARATE

SALT/SOLVATE -> PARENT

Amount:


					PUO0521HZV

CYTOCHROME P450 3A4

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MAJOR


					1PE72K8X46

MU-TYPE OPIOID RECEPTOR

TARGET -> AGONIST


					081I12ZA58

CYTOCHROME P450 2C19

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MINOR


					8E4LAA4357

CYTOCHROME P450 2D6

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MAJOR


					MCN858TCP0

EXCRETED UNCHANGED

Qualification:

URINE

Amount:

Related Record Type Details


					TEG0D9299T

METABOLITE -> PARENT

Qualification:

PLASMA

Amount:


					6UDH2YDN71

(3S,5R,7R)-7-(2-((3-METHOXY-2-THIENYL)METHYLAMINO)ETHYL)-7-(2-PYRIDYL)-10-OXASPIRO(4.5)DECAN-3-OL

METABOLITE -> PARENT

Qualification:

URINE

Amount:

Related Record Type Details


					MCN858TCP0

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC				AT STEADY-STATE

Tmax	PHARMACOKINETIC				SINGLE DOSE INTRAVENOUS ADMINISTRATION

Biological Half-life	PHARMACOKINETIC				INTRAVENOUS ADMINISTRATION SINGLE DOSE