U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:17:02 GMT 2023
Edited
by admin
on Sat Dec 16 14:17:02 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
MA05AF40UO
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PIMIVALIMAB
USAN   INN  
Official Name English
PIMIVALIMAB [USAN]
Common Name English
pimivalimab [INN]
Common Name English
IMMUNOGLOBULIN G4 (226-PROLINE,C-TERMINAL-LYSINE-CLIPPED), ANTI-(HUMAN PROGRAMMED CELL DEATH PROTEIN 1) (HUMAN MONOCLONAL JTX-4014 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL JTX-4014 .KAPPA.-CHAIN, DIMER
Common Name English
JTX-4014
Code English
Pimivalimab [WHO-DD]
Common Name English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS PROGRAMMED CELL DEATH 1 LIGAND 1 (PD-L1; CD274 ANTIGEN)); HUMAN MONOCLONAL ANTIBODY; .GAMMA.4 HEAVY CHAIN HOMO SAPIENS (1-444) (VH HOMO SAPIENS (IGHV1-46*01 (97%) (IGHD)-IGHJ5*02) (8.8.11) (1-118)-HOMO SAPIENS
Common Name English
Code System Code Type Description
NCI_THESAURUS
C157485
Created by admin on Sat Dec 16 14:17:02 GMT 2023 , Edited by admin on Sat Dec 16 14:17:02 GMT 2023
PRIMARY
CAS
2245092-16-2
Created by admin on Sat Dec 16 14:17:02 GMT 2023 , Edited by admin on Sat Dec 16 14:17:02 GMT 2023
NO STRUCTURE GIVEN
FDA UNII
MA05AF40UO
Created by admin on Sat Dec 16 14:17:02 GMT 2023 , Edited by admin on Sat Dec 16 14:17:02 GMT 2023
PRIMARY
USAN
JK-140
Created by admin on Sat Dec 16 14:17:02 GMT 2023 , Edited by admin on Sat Dec 16 14:17:02 GMT 2023
PRIMARY
INN
11461
Created by admin on Sat Dec 16 14:17:02 GMT 2023 , Edited by admin on Sat Dec 16 14:17:02 GMT 2023
PRIMARY
CAS
2293951-22-9
Created by admin on Sat Dec 16 14:17:02 GMT 2023 , Edited by admin on Sat Dec 16 14:17:02 GMT 2023
PRIMARY
From To
1_22 1_96
1_132 1_145
1_201 3_214
1_224 2_224
1_227 2_227
1_259 1_319
1_365 1_423
2_22 2_96
2_132 2_145
2_201 4_214
2_259 2_319
2_365 2_423
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Link Type Site
N 1_295
N 2_295
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL