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Approval Year

Substance Class Protein
Created
by admin
on Fri Jun 25 21:36:22 UTC 2021
Edited
by admin
on Fri Jun 25 21:36:22 UTC 2021
Protein Type RECEPTOR
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
938DNF64FO
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PROGRAMMED CELL DEATH PROTEIN 1
Common Name English
PDCD1
Common Name English
SYSTEMIC LUPUS ERYTHEMATOSUS SUSCEPTIBILITY 2
Common Name English
CD279
Common Name English
HPD-1
Common Name English
CD-279
Common Name English
PROTEIN PD-1
Common Name English
PD-1
Common Name English
Code System Code Type Description
FDA UNII
938DNF64FO
Created by admin on Fri Jun 25 21:36:22 UTC 2021 , Edited by admin on Fri Jun 25 21:36:22 UTC 2021
PRIMARY
WIKIPEDIA
PROGRAMMED CELL DEATH PROTEIN 1
Created by admin on Fri Jun 25 21:36:22 UTC 2021 , Edited by admin on Fri Jun 25 21:36:22 UTC 2021
PRIMARY
UNIPROT
Q15116
Created by admin on Fri Jun 25 21:36:22 UTC 2021 , Edited by admin on Fri Jun 25 21:36:22 UTC 2021
PRIMARY
GENE
5133
Created by admin on Fri Jun 25 21:36:22 UTC 2021 , Edited by admin on Fri Jun 25 21:36:22 UTC 2021
PRIMARY
From To
1_34 1_103
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_29
N 1_38
N 1_54
N 1_96
Related Record Type Details
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
AGONIST -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
(Biacore) Antigens were immobilized on a sensor chip, and varying concentrations of AK105 (1.56 to 50 nM) were flown over immobilized PD-1 at the flow rate of 30 ?L/min.
BINDING
Kd
INHIBITOR -> TARGET
AGONIST -> TARGET
PD-L2 binds to its receptor PD-1 with dissociation constant Kd of 11.3 nM.[16] Binding to PD-1 can activate pathways inhibiting TCR/BCR-mediated immune cell activation
BINDING
Kd
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL