U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 11:57:38 GMT 2023
Edited
by admin
on Sat Dec 16 11:57:38 GMT 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
M4PJ7V12VY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BDNF/NT-3 GROWTH FACTORS RECEPTOR
Common Name English
NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE 2
Common Name English
TRKB
Common Name English
TROPOMYOSIN-RELATED KINASE B
Common Name English
GP145-TRKB
Common Name English
TROPOMYOSIN RECEPTOR KINASE B
Common Name English
TYROSINE RECEPTOR KINASE B
Common Name English
NTRK2
Common Name English
Code System Code Type Description
UNIPROT
Q16620
Created by admin on Sat Dec 16 11:57:39 GMT 2023 , Edited by admin on Sat Dec 16 11:57:39 GMT 2023
PRIMARY
FDA UNII
M4PJ7V12VY
Created by admin on Sat Dec 16 11:57:39 GMT 2023 , Edited by admin on Sat Dec 16 11:57:39 GMT 2023
PRIMARY
From To
1_1 1_7
1_5 1_14
1_121 1_145
1_123 1_163
1_187 1_235
1_271 1_314
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_36
N 1_64
N 1_90
N 1_147
N 1_174
N 1_210
N 1_223
N 1_249
N 1_294
N 1_307
N 1_381
Related Record Type Details
INHIBITOR -> TARGET
ANTAGONIST
PARTIAL AGONIST->TARGET
INHIBITOR -> TARGET
IC50
INHIBITOR -> TARGET
COMPETITIVE INHIBITOR
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
IC50
AGONIST -> TARGET
INHIBITOR -> TARGET
IC50
RADIOLIGAND->TARGET
Through a panel of 369 human kinases (no detectable kinase off-target at 1000-fold concentration over TrkB/C potency)
IC50
AGONIST -> TARGET
AGONIST -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
IC50
AGONIST -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
AGONIST -> TARGET
INHIBITOR -> TARGET
IC50
INHIBITOR -> TARGET
AGONIST -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL