LM22A-4

OCCNC(=O)C1=CC(=CC(=C1)C(=O)NCCO)C(=O)NCCO

InChIKey=RGWJKANXFYJKHN-UHFFFAOYSA-N

InChI=1S/C15H21N3O6/c19-4-1-16-13(22)10-7-11(14(23)17-2-5-20)9-12(8-10)15(24)18-3-6-21/h7-9,19-21H,1-6H2,(H,16,22)(H,17,23)(H,18,24)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
BDNF/NT-3 growth factors receptor 4 Target ID: Q16620 Gene ID: 4915.0 Gene Symbol: NTRK2 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/20407211	Agonist 2678		47.0 nM [IC50]

PubMed

Title	Date	PubMed
Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents.	2010 May	20407211

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:36:10 GMT 2023` Edited by `admin` on `Sat Dec 16 17:36:10 GMT 2023`
Record UNII	5GCL3P6AF5
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

LM22A-4

Code

English

LM22A4

Code

English

N1,N3,N5-Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide

Systematic Name

English

LM-22A4

Code

English

1,3,5-Benzenetricarboxamide, N,N′,N′′-tris(2-hydroxyethyl)-

Systematic Name

English

1,3,5-Benzenetricarboxamide, N1,N3,N5-tris(2-hydroxyethyl)-

Systematic Name

English

1-N,3-N,5-N-Tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide

Systematic Name

English

Code System Code Type Description

PUBCHEM

2054170