Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C25H29N3O4 |
| Molecular Weight | 435.5155 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O[C@@H](CNCCC1=CC=C(NC[C@H](O)C2=CC=CC=C2)C=C1)C3=CC=C(O)C(NC=O)=C3
InChI
InChIKey=BMKINZUHKYLSKI-DQEYMECFSA-N
InChI=1S/C25H29N3O4/c29-17-28-22-14-20(8-11-23(22)30)24(31)15-26-13-12-18-6-9-21(10-7-18)27-16-25(32)19-4-2-1-3-5-19/h1-11,14,17,24-27,30-32H,12-13,15-16H2,(H,28,29)/t24-,25-/m0/s1
| Molecular Formula | C25H29N3O4 |
| Molecular Weight | 435.5155 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Milveterol (also known as GSK159797) was developed as a longer-acting beta2 adrenoceptor agonist for the treatment of respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). Milveterol completed phase II clinical trials for asthmatic subjects. However further development of the drug was discontinued.
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Bronchodilating drugs for chronic obstructive pulmonary disease: current status and future trends. | 2015-05-28 |
|
| A multivalent approach to the discovery of long-acting β(2)-adrenoceptor agonists for the treatment of asthma and COPD. | 2012-01-15 |
|
| Novel bronchodilators in asthma. | 2010-01 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 08:31:49 GMT 2025
by
admin
on
Wed Apr 02 08:31:49 GMT 2025
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| Record UNII |
LGY1VQ9622
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| Record Status |
Validated (UNII)
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| Record Version |
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NCI_THESAURUS |
C48149
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C77935
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CHEMBL1940832
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DTXSID30215640
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| Related Record | Type | Details | ||
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SALT/SOLVATE -> PARENT |
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TARGET -> AGONIST |
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ACTIVE MOIETY |
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