Nezutatug

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 19:33:53 GMT 2023` Edited by `admin` on `Sat Dec 16 19:33:53 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	HZZ2SGC2TW
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Nezutatug

Official Name

English

Gamma1 heavy chain humanized (1-450) [VH (Homo sapiens IGHV4-31*01 (89.9%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [9.7.13] (26-34.52-58.97-109)) (1-120) -Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, D12, L14 (CH1 K120 (217) (121-218), hinge 1-15 (219-233

Common Name

English

nezutatug [INN]

Common Name

English

Nezutatug (Immunoglobulin G1-kappa, anti-[Homo sapiens ERBB3 (receptor tyrosine-protein kinase erbB-3, HER3)], humanized monoclonal antibody)

Common Name

English

Immunoglobulin G1, anti-(human epidermal growth factor receptor HER3) (human-Mus musculus monoclonal HMBD-001 γ1-chain), disulfide with human-Mus musculus monoclonal HMBD-001 κ-chain, dimer

Common Name

English

HMBD-001

Code

English

Code System Code Type Description

INN

12596

Created by admin on Sat Dec 16 19:33:53 GMT 2023 , Edited by admin on Sat Dec 16 19:33:53 GMT 2023

PRIMARY

FDA UNII

HZZ2SGC2TW

Created by admin on Sat Dec 16 19:33:53 GMT 2023 , Edited by admin on Sat Dec 16 19:33:53 GMT 2023

PRIMARY

NCI_THESAURUS

C199011

Created by admin on Sat Dec 16 19:33:53 GMT 2023 , Edited by admin on Sat Dec 16 19:33:53 GMT 2023

PRIMARY

CAS

2673271-78-6

Created by admin on Sat Dec 16 19:33:53 GMT 2023 , Edited by admin on Sat Dec 16 19:33:53 GMT 2023

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_147	2_203
2_223	4_214
2_264	2_324
1_147	1_203
2_370	2_428
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_223	3_214
1_229	2_229
1_232	2_232
1_264	1_324
1_370	1_428

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_300
N	2_300

Related Record Type Details


					RSO83C9PIA

RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3

TARGET->LIGAND

Amount:

Related Record Type Details


					HZZ2SGC2TW

Nezutatug

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL