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Details

Stereochemistry RACEMIC
Molecular Formula C18H22BrNO
Molecular Weight 348.2776
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of EMBRAMINE

SMILES

CC(c1ccccc1)(c2ccc(cc2)Br)OCCN(C)C

InChI

InChIKey=URSRSKSNFPUKGH-UHFFFAOYSA-N
InChI=1S/C18H22BrNO/c1-18(21-14-13-20(2)3,15-7-5-4-6-8-15)16-9-11-17(19)12-10-16/h4-12H,13-14H2,1-3H3

HIDE SMILES / InChI

Molecular Formula C18H22BrNO
Molecular Weight 348.2776
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Embramine or mebrophenhydramine is an antiallergic agent. Embramine is a histamine H₁-receptor antagonist exerting anticholinergic activity. It may inhibit stimulated platelet functions by inhibiting phospholipase A2. It is prescribed for severe allergic conditions.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
PubMed

PubMed

TitleDatePubMed
Pharmacological intervention with platelet phospholipase A2.
2001
Titrimetric and spectrophotometric assay of some antihistamines through the determination of the chloride of their hydrochlorides.
2002 Jan
H(1)- antihistamines and activated blood platelets.
2006 Apr
Patents

Patents

Sample Use Guides

The recommended dose is 25mg, every 4 to 6 hours. Max: 150mg.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Jun 26 02:12:44 UTC 2021
Edited
by admin
on Sat Jun 26 02:12:44 UTC 2021
Record UNII
HH0KD7Z416
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
EMBRAMINE
INN   MI   WHO-DD  
INN  
Official Name English
EMBRAMINE [INN]
Common Name English
EMBRAMINE [MI]
Common Name English
EMBRAMINE [WHO-DD]
Common Name English
2-((P-BROMO-.ALPHA.-METHYL-.ALPHA.-PHENYLBENZYL)OXY)-N,N-DIMETHYLETHYLAMINE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29578
Created by admin on Sat Jun 26 02:12:45 UTC 2021 , Edited by admin on Sat Jun 26 02:12:45 UTC 2021
Code System Code Type Description
DRUG CENTRAL
998
Created by admin on Sat Jun 26 02:12:45 UTC 2021 , Edited by admin on Sat Jun 26 02:12:45 UTC 2021
PRIMARY
NCI_THESAURUS
C81150
Created by admin on Sat Jun 26 02:12:45 UTC 2021 , Edited by admin on Sat Jun 26 02:12:45 UTC 2021
PRIMARY
EVMPD
SUB06500MIG
Created by admin on Sat Jun 26 02:12:45 UTC 2021 , Edited by admin on Sat Jun 26 02:12:45 UTC 2021
PRIMARY
INN
1784
Created by admin on Sat Jun 26 02:12:45 UTC 2021 , Edited by admin on Sat Jun 26 02:12:45 UTC 2021
PRIMARY
MESH
C005715
Created by admin on Sat Jun 26 02:12:45 UTC 2021 , Edited by admin on Sat Jun 26 02:12:45 UTC 2021
PRIMARY
PUBCHEM
19105
Created by admin on Sat Jun 26 02:12:45 UTC 2021 , Edited by admin on Sat Jun 26 02:12:45 UTC 2021
PRIMARY
MERCK INDEX
M1131
Created by admin on Sat Jun 26 02:12:45 UTC 2021 , Edited by admin on Sat Jun 26 02:12:45 UTC 2021
PRIMARY Merck Index
CAS
3565-72-8
Created by admin on Sat Jun 26 02:12:45 UTC 2021 , Edited by admin on Sat Jun 26 02:12:45 UTC 2021
PRIMARY
ChEMBL
CHEMBL2110819
Created by admin on Sat Jun 26 02:12:45 UTC 2021 , Edited by admin on Sat Jun 26 02:12:45 UTC 2021
PRIMARY
FDA UNII
HH0KD7Z416
Created by admin on Sat Jun 26 02:12:45 UTC 2021 , Edited by admin on Sat Jun 26 02:12:45 UTC 2021
PRIMARY
WIKIPEDIA
EMBRAMINE
Created by admin on Sat Jun 26 02:12:45 UTC 2021 , Edited by admin on Sat Jun 26 02:12:45 UTC 2021
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
ENANTIOMER -> RACEMATE
SALT/SOLVATE -> PARENT
ENANTIOMER -> RACEMATE
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY