EMBRAMINE

Details

Stereochemistry	RACEMIC
Molecular Formula	C18H22BrNO
Molecular Weight	348.277
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C)CCOC(C)(C1=CC=CC=C1)C2=CC=C(Br)C=C2

InChI

InChIKey=URSRSKSNFPUKGH-UHFFFAOYSA-N

InChI=1S/C18H22BrNO/c1-18(21-14-13-20(2)3,15-7-5-4-6-8-15)16-9-11-17(19)12-10-16/h4-12H,13-14H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C18H22BrNO
Molecular Weight	348.277
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.medindia.net/doctors/drug_information/embramine.htm | https://www.drugs.com/international/embramine.html | https://www.ncbi.nlm.nih.gov/pubmed/7976789

Embramine or mebrophenhydramine is an antiallergic agent. Embramine is a histamine H₁-receptor antagonist exerting anticholinergic activity. It may inhibit stimulated platelet functions by inhibiting phospholipase A2. It is prescribed for severe allergic conditions.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Histamine H1 receptor 316 Target ID: CHEMBL231 Sources: https://www.ncbi.nlm.nih.gov/pubmed/7758143	Antagonist 2849

PubMed

Title	Date	PubMed
H(1)- antihistamines and activated blood platelets.	2006-04	16547813
Cationic amphiphilic drugs and platelet phospholipase A(2) (cPLA(2)).	2002-02-15	12031829
Titrimetric and spectrophotometric assay of some antihistamines through the determination of the chloride of their hydrochlorides.	2002-01	11902650
Vitrification of mouse oocytes using a nylon loop.	2001-03	11170276
Pharmacological intervention with platelet phospholipase A2.	2001	11802290

Patents

Sample Use Guides

In Vivo Use Guide

The recommended dose is 25mg, every 4 to 6 hours. Max: 150mg.

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Wed Apr 02 09:53:16 GMT 2025` Edited by `admin` on `Wed Apr 02 09:53:16 GMT 2025`
Record UNII	HH0KD7Z416
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

EMBRAMINE [MI]

Preferred Name

English

EMBRAMINE

Official Name

English

embramine [INN]

Common Name

English

Embramine [WHO-DD]

Common Name

English

2-((P-BROMO-.ALPHA.-METHYL-.ALPHA.-PHENYLBENZYL)OXY)-N,N-DIMETHYLETHYLAMINE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29578