EMBRAMINE HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C18H22BrNO.ClH
Molecular Weight	384.738
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CN(C)CCOC(C)(C1=CC=CC=C1)C2=CC=C(Br)C=C2

InChI

InChIKey=JUOZATSMKDYYGH-UHFFFAOYSA-N

InChI=1S/C18H22BrNO.ClH/c1-18(21-14-13-20(2)3,15-7-5-4-6-8-15)16-9-11-17(19)12-10-16;/h4-12H,13-14H2,1-3H3;1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C18H22BrNO
Molecular Weight	348.277
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.medindia.net/doctors/drug_information/embramine.htm | https://www.drugs.com/international/embramine.html | https://www.ncbi.nlm.nih.gov/pubmed/7976789

Embramine or mebrophenhydramine is an antiallergic agent. Embramine is a histamine H₁-receptor antagonist exerting anticholinergic activity. It may inhibit stimulated platelet functions by inhibiting phospholipase A2. It is prescribed for severe allergic conditions.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Histamine H1 receptor 315 Target ID: CHEMBL231 Sources: https://www.ncbi.nlm.nih.gov/pubmed/7758143	Antagonist 2778

PubMed

Title	Date	PubMed
Vitrification of mouse oocytes using a nylon loop.	2001 Mar	11170276

Patents

Sample Use Guides

In Vivo Use Guide

The recommended dose is 25mg, every 4 to 6 hours. Max: 150mg.

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:17:15 UTC 2023` Edited by `admin` on `Fri Dec 15 17:17:15 UTC 2023`
Record UNII	7BJ3V657VC
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

EMBRAMINE HYDROCHLORIDE

Common Name

English

MEBROPHENHYDRAMINE HYDROCHLORIDE

Common Name

English

EMBRAMINE HYDROCHLORIDE [MI]

Common Name

English

EMBRAMINE HYDROCHLORIDE [MART.]

Common Name

English

Embramine hydrochloride [WHO-DD]

Common Name

English

2-((P-BROMO-.ALPHA.-METHYL-.ALPHA.-PHENYLBENZYL)OXY)-N,N-DIMETHYLETHYLAMINE HYDROCHLORIDE

Common Name

English

EMBRAMINE HCL

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29578