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Details

Stereochemistry RACEMIC
Molecular Formula C18H22BrNO.ClH
Molecular Weight 384.738
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of EMBRAMINE HYDROCHLORIDE

SMILES

Cl.CN(C)CCOC(C)(C1=CC=CC=C1)C2=CC=C(Br)C=C2

InChI

InChIKey=JUOZATSMKDYYGH-UHFFFAOYSA-N
InChI=1S/C18H22BrNO.ClH/c1-18(21-14-13-20(2)3,15-7-5-4-6-8-15)16-9-11-17(19)12-10-16;/h4-12H,13-14H2,1-3H3;1H

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C18H22BrNO
Molecular Weight 348.277
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Embramine or mebrophenhydramine is an antiallergic agent. Embramine is a histamine H₁-receptor antagonist exerting anticholinergic activity. It may inhibit stimulated platelet functions by inhibiting phospholipase A2. It is prescribed for severe allergic conditions.

Approval Year

Unknown
139,594

Targets

Primary TargetPharmacologyConditionPotency
Histamine H1 receptor
315
Antagonist
2,778

PubMed

Patents

20040224012
20

Sample Use Guides

In Vivo Use Guide
The recommended dose is 25mg, every 4 to 6 hours. Max: 150mg.
Route of Administration: Oral
Substance Class Chemical
Record UNII
7BJ3V657VC
Record Status Validated (UNII)
Record Version
NIH
NCATS
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