Lipustobart

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 04:51:48 GMT 2025` Edited by `admin` on `Wed Apr 02 04:51:48 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	H6KN31H3XF
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ANTI-PD-1 MONOCLONAL ANTIBODY LZM009

Preferred Name

English

Lipustobart

Official Name

English

lipustobart [INN]

Common Name

English

Immunoglobulin G4 [228-proline], anti-(human programmed cell death protein 1) (human-Mus musculus monoclonal LZM009 ?4-chain), disulfide with human-Mus musculus monoclonal LZM009 ?-chain, dimer

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C129822

Created by admin on Wed Apr 02 04:51:48 GMT 2025 , Edited by admin on Wed Apr 02 04:51:48 GMT 2025

NCI_THESAURUS

C128037

Created by admin on Wed Apr 02 04:51:48 GMT 2025 , Edited by admin on Wed Apr 02 04:51:48 GMT 2025

Code System Code Type Description

NCI_THESAURUS

C153149

Created by admin on Wed Apr 02 04:51:48 GMT 2025 , Edited by admin on Wed Apr 02 04:51:48 GMT 2025

PRIMARY

NCIT

SMS_ID

300000046867

Created by admin on Wed Apr 02 04:51:48 GMT 2025 , Edited by admin on Wed Apr 02 04:51:48 GMT 2025

PRIMARY

CAS

2639481-06-2

Created by admin on Wed Apr 02 04:51:48 GMT 2025 , Edited by admin on Wed Apr 02 04:51:48 GMT 2025

PRIMARY

INN

12392

Created by admin on Wed Apr 02 04:51:48 GMT 2025 , Edited by admin on Wed Apr 02 04:51:48 GMT 2025

PRIMARY

FDA UNII

H6KN31H3XF

Created by admin on Wed Apr 02 04:51:48 GMT 2025 , Edited by admin on Wed Apr 02 04:51:48 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
3_23	3_92
4_23	4_92
1_134	3_218
2_134	4_218
3_138	3_198
4_138	4_198
1_147	1_203
2_147	2_203
1_226	2_226
1_229	2_229
1_261	1_321
2_261	2_321
1_367	1_425
2_367	2_425

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_297
N	2_297

Related Record Type Details


					938DNF64FO

PROGRAMMED CELL DEATH PROTEIN 1

TARGET -> INHIBITOR

Qualification:

Kd

Amount:

Related Record Type Details


					H6KN31H3XF

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_447] [2_447]	C-TERMINUS			LYSINE	K3Z4F929H6
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL