U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C14H18As2N2O6
Molecular Weight 460.1457
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIFETARSONE

SMILES

O[As](O)(=O)C1=CC=C(NCCNC2=CC=C(C=C2)[As](O)(O)=O)C=C1

InChI

InChIKey=YQVALJGIKVYRNI-UHFFFAOYSA-N
InChI=1S/C14H18As2N2O6/c19-15(20,21)11-1-5-13(6-2-11)17-9-10-18-14-7-3-12(4-8-14)16(22,23)24/h1-8,17-18H,9-10H2,(H2,19,20,21)(H2,22,23,24)

HIDE SMILES / InChI

Molecular Formula C14H18As2N2O6
Molecular Weight 460.1457
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Difetarsone, an anthelmintic drug, was used in the treatment of Trichuris trichiura (whipworm) infestation.

Approval Year

Sample Use Guides

The mothers of patients in group A were instructed to give the children a single daily dose of difetarsone on each of the following 5 days. The daily dose was calculated at 50 mg/kg per day and the exact number of tablets was supplied for the 5-day course. The mothers of
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:08:42 GMT 2023
Edited
by admin
on Fri Dec 15 16:08:42 GMT 2023
Record UNII
G4G9J3Q65W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DIFETARSONE
INN   WHO-DD  
INN  
Official Name English
RP 4763 ANHYDROUS FREE ACID
Code English
difetarsone [INN]
Common Name English
Difetarsone [WHO-DD]
Common Name English
RP-4763 ANHYDROUS FREE ACID
Code English
N,N-ETHYLENEDIARSANILIC ACID
Common Name English
DIPHETARSONE
Common Name English
Classification Tree Code System Code
WHO-ATC P01AR02
Created by admin on Fri Dec 15 16:08:42 GMT 2023 , Edited by admin on Fri Dec 15 16:08:42 GMT 2023
WHO-VATC QP51AD02
Created by admin on Fri Dec 15 16:08:42 GMT 2023 , Edited by admin on Fri Dec 15 16:08:42 GMT 2023
Code System Code Type Description
MESH
C037924
Created by admin on Fri Dec 15 16:08:42 GMT 2023 , Edited by admin on Fri Dec 15 16:08:42 GMT 2023
PRIMARY
INN
3219
Created by admin on Fri Dec 15 16:08:42 GMT 2023 , Edited by admin on Fri Dec 15 16:08:42 GMT 2023
PRIMARY
DRUG CENTRAL
4419
Created by admin on Fri Dec 15 16:08:42 GMT 2023 , Edited by admin on Fri Dec 15 16:08:42 GMT 2023
PRIMARY
EVMPD
SUB07124MIG
Created by admin on Fri Dec 15 16:08:42 GMT 2023 , Edited by admin on Fri Dec 15 16:08:42 GMT 2023
PRIMARY
NCI_THESAURUS
C78101
Created by admin on Fri Dec 15 16:08:42 GMT 2023 , Edited by admin on Fri Dec 15 16:08:42 GMT 2023
PRIMARY
CAS
3639-19-8
Created by admin on Fri Dec 15 16:08:42 GMT 2023 , Edited by admin on Fri Dec 15 16:08:42 GMT 2023
PRIMARY
FDA UNII
G4G9J3Q65W
Created by admin on Fri Dec 15 16:08:42 GMT 2023 , Edited by admin on Fri Dec 15 16:08:42 GMT 2023
PRIMARY
DRUG BANK
DB13599
Created by admin on Fri Dec 15 16:08:42 GMT 2023 , Edited by admin on Fri Dec 15 16:08:42 GMT 2023
PRIMARY
RXCUI
402587
Created by admin on Fri Dec 15 16:08:42 GMT 2023 , Edited by admin on Fri Dec 15 16:08:42 GMT 2023
PRIMARY RxNorm
EPA CompTox
DTXSID30189913
Created by admin on Fri Dec 15 16:08:42 GMT 2023 , Edited by admin on Fri Dec 15 16:08:42 GMT 2023
PRIMARY
PUBCHEM
68199
Created by admin on Fri Dec 15 16:08:42 GMT 2023 , Edited by admin on Fri Dec 15 16:08:42 GMT 2023
PRIMARY
SMS_ID
100000083155
Created by admin on Fri Dec 15 16:08:42 GMT 2023 , Edited by admin on Fri Dec 15 16:08:42 GMT 2023
PRIMARY
ECHA (EC/EINECS)
222-866-0
Created by admin on Fri Dec 15 16:08:42 GMT 2023 , Edited by admin on Fri Dec 15 16:08:42 GMT 2023
PRIMARY
WIKIPEDIA
Difetarsone
Created by admin on Fri Dec 15 16:08:42 GMT 2023 , Edited by admin on Fri Dec 15 16:08:42 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY