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Details

Stereochemistry ACHIRAL
Molecular Formula C14H16As2N2O6.2Na
Molecular Weight 504.1094
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIFETARSONE SODIUM ANHYDROUS

SMILES

[Na+].[Na+].O[As]([O-])(=O)C1=CC=C(NCCNC2=CC=C(C=C2)[As](O)([O-])=O)C=C1

InChI

InChIKey=WJQJTJQDBFMBJM-UHFFFAOYSA-L
InChI=1S/C14H18As2N2O6.2Na/c19-15(20,21)11-1-5-13(6-2-11)17-9-10-18-14-7-3-12(4-8-14)16(22,23)24;;/h1-8,17-18H,9-10H2,(H2,19,20,21)(H2,22,23,24);;/q;2*+1/p-2

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
MOL RATIO 2 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C14H16As2N2O6
Molecular Weight 458.1298
Charge -2
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Difetarsone, an anthelmintic drug, was used in the treatment of Trichuris trichiura (whipworm) infestation.

Approval Year

Sample Use Guides

In Vivo Use Guide
The mothers of patients in group A were instructed to give the children a single daily dose of difetarsone on each of the following 5 days. The daily dose was calculated at 50 mg/kg per day and the exact number of tablets was supplied for the 5-day course. The mothers of
Route of Administration: Oral
Substance Class Chemical
Record UNII
KSF0S7W3I7
Record Status Validated (UNII)
Record Version