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Details

Stereochemistry ACHIRAL
Molecular Formula C14H16As2N2O6.2Na
Molecular Weight 504.1094
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIFETARSONE SODIUM ANHYDROUS

SMILES

[Na+].[Na+].O[As]([O-])(=O)C1=CC=C(NCCNC2=CC=C(C=C2)[As](O)([O-])=O)C=C1

InChI

InChIKey=WJQJTJQDBFMBJM-UHFFFAOYSA-L
InChI=1S/C14H18As2N2O6.2Na/c19-15(20,21)11-1-5-13(6-2-11)17-9-10-18-14-7-3-12(4-8-14)16(22,23)24;;/h1-8,17-18H,9-10H2,(H2,19,20,21)(H2,22,23,24);;/q;2*+1/p-2

HIDE SMILES / InChI
Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C14H16As2N2O6
Molecular Weight 458.1298
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Difetarsone, an anthelmintic drug, was used in the treatment of Trichuris trichiura (whipworm) infestation.

Approval Year

Unknown
139594

Sample Use Guides

In Vivo Use Guide
The mothers of patients in group A were instructed to give the children a single daily dose of difetarsone on each of the following 5 days. The daily dose was calculated at 50 mg/kg per day and the exact number of tablets was supplied for the 5-day course. The mothers of
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 20:38:43 GMT 2023
Edited
by admin
on Fri Dec 15 20:38:43 GMT 2023
Record UNII
KSF0S7W3I7
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DIFETARSONE SODIUM ANHYDROUS
Common Name English
DIPHETARSONE [MI]
Common Name English
DISODIUM N,N'-ETHYLENEBIS(4-AMINOPHENYLARSONATE)
Systematic Name English
Difetarsone sodium [WHO-DD]
Common Name English
ANHYDROUS DIFETARSONE SODIUM
MART.  
Common Name English
ARSONIC ACID, (1,2-ETHANEDIYLBIS(IMINO-4,1-PHENYLENE))BIS-, DISODIUM SALT
Common Name English
ANHYDROUS DIFETARSONE SODIUM [MART.]
Common Name English
Code System Code Type Description
PUBCHEM
68198
Created by admin on Fri Dec 15 20:38:43 GMT 2023 , Edited by admin on Fri Dec 15 20:38:43 GMT 2023
PRIMARY
ECHA (EC/EINECS)
208-209-0
Created by admin on Fri Dec 15 20:38:43 GMT 2023 , Edited by admin on Fri Dec 15 20:38:43 GMT 2023
PRIMARY
CAS
515-76-4
Created by admin on Fri Dec 15 20:38:43 GMT 2023 , Edited by admin on Fri Dec 15 20:38:43 GMT 2023
PRIMARY
EPA CompTox
DTXSID90965831
Created by admin on Fri Dec 15 20:38:43 GMT 2023 , Edited by admin on Fri Dec 15 20:38:43 GMT 2023
PRIMARY
FDA UNII
KSF0S7W3I7
Created by admin on Fri Dec 15 20:38:43 GMT 2023 , Edited by admin on Fri Dec 15 20:38:43 GMT 2023
PRIMARY
MERCK INDEX
m706
Created by admin on Fri Dec 15 20:38:43 GMT 2023 , Edited by admin on Fri Dec 15 20:38:43 GMT 2023
PRIMARY Merck Index
Related Record Type Details
Structure of DIFETARSONE SODIUM
SOLVATE->ANHYDROUS
Structure of DIFETARSONE
PARENT -> SALT/SOLVATE
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