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Details

Stereochemistry ACHIRAL
Molecular Formula C14H16As2N2O6.2Na.10H2O
Molecular Weight 684.2622
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIFETARSONE SODIUM

SMILES

O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].O[As]([O-])(=O)C1=CC=C(NCCNC2=CC=C(C=C2)[As](O)([O-])=O)C=C1

InChI

InChIKey=JYNLGGBUYRVSMO-UHFFFAOYSA-L
InChI=1S/C14H18As2N2O6.2Na.10H2O/c19-15(20,21)11-1-5-13(6-2-11)17-9-10-18-14-7-3-12(4-8-14)16(22,23)24;;;;;;;;;;;;/h1-8,17-18H,9-10H2,(H2,19,20,21)(H2,22,23,24);;;10*1H2/q;2*+1;;;;;;;;;;/p-2

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
MOL RATIO 2 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
MOL RATIO 10 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C14H18As2N2O6
Molecular Weight 460.1457
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Difetarsone, an anthelmintic drug, was used in the treatment of Trichuris trichiura (whipworm) infestation.

Approval Year

Sample Use Guides

In Vivo Use Guide
The mothers of patients in group A were instructed to give the children a single daily dose of difetarsone on each of the following 5 days. The daily dose was calculated at 50 mg/kg per day and the exact number of tablets was supplied for the 5-day course. The mothers of
Route of Administration: Oral
Substance Class Chemical
Record UNII
50LJ8395PN
Record Status Validated (UNII)
Record Version