DIFETARSONE SODIUM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H16As2N2O6.2Na.10H2O
Molecular Weight	684.2622
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].O[As]([O-])(=O)C1=CC=C(NCCNC2=CC=C(C=C2)[As](O)([O-])=O)C=C1

InChI

InChIKey=JYNLGGBUYRVSMO-UHFFFAOYSA-L

InChI=1S/C14H18As2N2O6.2Na.10H2O/c19-15(20,21)11-1-5-13(6-2-11)17-9-10-18-14-7-3-12(4-8-14)16(22,23)24;;;;;;;;;;;;/h1-8,17-18H,9-10H2,(H2,19,20,21)(H2,22,23,24);;;10*1H2/q;2*+1;;;;;;;;;;/p-2

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C14H18As2N2O6
Molecular Weight	460.1457
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4825661

Difetarsone, an anthelmintic drug, was used in the treatment of Trichuris trichiura (whipworm) infestation.

Approval Year

Sample Use Guides

In Vivo Use Guide

The mothers of patients in group A were instructed to give the children a single daily dose of difetarsone on each of the following 5 days. The daily dose was calculated at 50 mg/kg per day and the exact number of tablets was supplied for the 5-day course. The mothers of

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 22:07:19 GMT 2023` Edited by `admin` on `Fri Dec 15 22:07:19 GMT 2023`
Record UNII	50LJ8395PN
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIFETARSONE SODIUM

Common Name

English

BEMARSAL

Brand Name

English

RP-4763

Code

English

DIFETARSONE SODIUM [MART.]

Common Name

English

DISODIUM N,N'-ETHYLENEBIS(4-AMINOPHENYLARSONATE) DECAHYDRATE

Systematic Name

English

Code System Code Type Description

CAS

5807-90-9