U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2014
494
Substance Class Protein
Created
by admin
on Sat Dec 16 04:49:34 GMT 2023
Edited
by admin
on Sat Dec 16 04:49:34 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
DPT0O3T46P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PEMBROLIZUMAB
DASH   INN   USAN   VANDF   WHO-DD  
USAN   INN  
Official Name English
PEMBROLIZUMAB [USAN]
Common Name English
PEMBROLIZUMAB [MI]
Common Name English
KEYTRUDA
Brand Name English
IMMUNOGLOBULIN G4, ANTI-(HUMAN PROTEIN PDCD1 (PROGRAMMED CELL DEATH 1)) (HUMAN-MUS MUSCULUS MONOCLONAL HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL LIGHT CHAIN, DIMER
Common Name English
KEYLYNK-010 COMPONENT PEMBROLIZUMAB
Code English
pembrolizumab [INN]
Common Name English
SCH-900475
Code English
PEMBROLIZUMAB COMPONENT OF KEYLYNK-010
Code English
LAMBROLIZUMAB
Common Name English
PEMBROLIZUMAB [VANDF]
Common Name English
MK 7684A COMPONENT PEMBROLIZUMAB
Common Name English
PEMBROLIZUMAB [PURPLE BOOK CDER]
Common Name English
MK-3475
Code English
MK-1308A COMPONENT PEMBROLIZUMAB
Common Name English
Pembrolizumab [WHO-DD]
Common Name English
PEMBROLIZUMAB [JAN]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 705319
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
FDA ORPHAN DRUG 502415
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
FDA ORPHAN DRUG 570816
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
FDA ORPHAN DRUG 578717
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
FDA ORPHAN DRUG 576917
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
FDA ORPHAN DRUG 511715
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
FDA ORPHAN DRUG 548216
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
WHO-ATC L01XC18
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
FDA ORPHAN DRUG 481715
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
FDA ORPHAN DRUG 605417
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
FDA ORPHAN DRUG 495415
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
FDA ORPHAN DRUG 381012
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
FDA ORPHAN DRUG 513115
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
EMA ASSESSMENT REPORTS KEYTRUDA (AUTHORIZED: MELANOMA)
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
NDF-RT N0000191260
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
NCI_THESAURUS C128037
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
Code System Code Type Description
FDA UNII
DPT0O3T46P
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
DRUG CENTRAL
4924
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
NDF-RT
N0000191259
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY Programmed Death Receptor-1-directed Antibody Interactions [MoA]
DAILYMED
DPT0O3T46P
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
MERCK INDEX
m11762
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
DRUG BANK
DB09037
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
CAS
1422183-02-5
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
SUPERSEDED
INN
9798
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
LACTMED
Pembrolizumab
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
SMS_ID
100000157957
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
CAS
1374853-91-4
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
RXCUI
1547545
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY RxNorm
IUPHAR
7499
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
ChEMBL
CHEMBL2364654
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
USAN
ZZ-165
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
HSDB
8257
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
WIKIPEDIA
Pembrolizumab
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
ChEMBL
CHEMBL3137343
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
EVMPD
SUB167136
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
NCI_THESAURUS
C106432
Created by admin on Sat Dec 16 04:49:34 GMT 2023 , Edited by admin on Sat Dec 16 04:49:34 GMT 2023
PRIMARY
From To
1_22 1_96
2_22 2_96
3_23 3_92
4_23 4_92
1_134 3_218
2_134 4_218
3_138 3_198
4_138 4_198
1_147 1_203
2_147 2_203
1_226 2_226
1_229 2_229
1_261 1_321
2_261 2_321
1_367 1_425
2_367 2_425
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_297
N 2_297
Related Record Type Details
PEMBROLIZUMAB DESFERRIOXAMINE ZIRCONIUM ZR-89
LABELED -> NON-LABELED
PROGRAMMED CELL DEATH PROTEIN 1
TARGET -> INHIBITOR
Related Record Type Details
PEMBROLIZUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Biological Half-life PHARMACOKINETIC
Molecular Formula CHEMICAL
Vdss PHARMACOKINETIC
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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