AZD-1390

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C27H32FN5O2
Molecular Weight	477.5737
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)N1C(=O)N(C)C2=C1C3=CC(C4=CN=C(OCCCN5CCCCC5)C=C4)=C(F)C=C3N=C2

InChI

InChIKey=VQSZIPCGAGVRRP-UHFFFAOYSA-N

InChI=1S/C27H32FN5O2/c1-18(2)33-26-21-14-20(22(28)15-23(21)29-17-24(26)31(3)27(33)34)19-8-9-25(30-16-19)35-13-7-12-32-10-5-4-6-11-32/h8-9,14-18H,4-7,10-13H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C27H32FN5O2
Molecular Weight	477.5737
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

CNS Activity

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Serine-protein kinase ATM 4 Target ID: Q13315 Gene ID: 472.0 Gene Symbol: ATM Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/29938225	Inhibitor 8228		0.78 nM [IC50]

PubMed

Title	Date	PubMed

Substance Class	Chemical Created by `admin` on `Thu Jul 06 19:37:15 UTC 2023` Edited by `admin` on `Thu Jul 06 19:37:15 UTC 2023`
Record UNII	CI43QFE22O
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

AZD-1390

Code

English

AZD1390

Code

English

7-FLUORO-1-ISOPROPYL-3-METHYL-8-(-(3-(1-PIPERIDINYL)PROPOXY)-3-PYRIDINYL)-1,3-DIHYDRO-2HIMIDAZO(4,5-C)QUINOLIN-2-ONE

Common Name

English

2H-IMIDAZO(4,5-C)QUINOLIN-2-ONE, 7-FLUORO-1,3-DIHYDRO-3-METHYL-1-(1-METHYLETHYL)-8-(6-(3-(1-PIPERIDINYL)PROPOXY)-3-PYRIDINYL)-

Systematic Name

English

AZD 1390 [WHO-DD]

Common Name

English

Code System Code Type Description

PUBCHEM

126689157