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Details

Stereochemistry ABSOLUTE
Molecular Formula C15H23NO
Molecular Weight 233.3492
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FAXELADOL

SMILES

CN(C)C[C@@H]1CCCC[C@H]1C2=CC(O)=CC=C2

InChI

InChIKey=JIRYWFYYBBRJAN-ZFWWWQNUSA-N
InChI=1S/C15H23NO/c1-16(2)11-13-6-3-4-9-15(13)12-7-5-8-14(17)10-12/h5,7-8,10,13,15,17H,3-4,6,9,11H2,1-2H3/t13-,15-/m0/s1

HIDE SMILES / InChI
Molecular Formula C15H23NO
Molecular Weight 233.3492
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Faxeladol (GRT9906) is a μ-opioid receptor agonist and inhibitor of noradrenalin/serotonin re-uptake. Faxeladol was being studied in the treatment of fibromyalgia and neuropathic pain, however its development has been discontinued.

Originator

Grunenthal
4

Approval Year

Unknown
139,594

PubMed

Patents

07884247
2
JP2004527491A
36
JP4737583B2
22

Sample Use Guides

In Vivo Use Guide
During 4-week treatment periods, daily oral doses of faxeladol (GRT9906) 120-240 mg
Route of Administration: Oral
Substance Class Chemical
Record UNII
C04V6SGK8H
Record Status Validated (UNII)
Record Version
NIH
NCATS
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