Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Tapentadol is the first US FDA-approved centrally acting analgesic having both μ-opioid receptor agonist and noradrenaline (norepinephrine) reuptake inhibition activity with minimal serotonin reuptake inhibition. Tapentadol is indicated for the manag...
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Tramadol (sold under the brand name Ultram) is a narcotic analgesic proposed for moderate to severe pain. Tramadol and its O-desmethyl metabolite (M1) are selective, weak OP3-receptor agonists. Opiate receptors are coupled with G-protein receptors an...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Butorphanol is a synthetic opioid agonist-antagonist analgesic with a pharmacological and therapeutic profile that has been well established since its launch as a parenteral formulation in 1978. The introduction of a transnasal formulation of butorph...
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Pentazocine is a synthetically prepared prototypical mixed agonist-antagonist narcotic (opioid analgesic) drug of the benzomorphan class of opioids used to treat moderate to moderately severe pain. Pentazocine is sold under several brand names, such ...
Faxeladol (GRT9906) is a μ-opioid receptor agonist and inhibitor of noradrenalin/serotonin re-uptake. Faxeladol was being studied in the treatment of fibromyalgia and neuropathic pain, however its development has been discontinued.
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Conditions:
Racemorphan is racemic mixture of an antitussive and dissociative hallucinogen Dextrorphan and an opioid analgesic Levorphanol. Racemorphan itself is under international control per the Single Convention on Narcotic Drugs 1961 and is therefore list...
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Nefopam (nefopam hydrochloride) is a potent, rapidly-acting non-narcotic analgesic. It is totally distinct from other centrally-acting analgesics such as morphine, codeine, pentazocine and propoxyphene. Unlike the narcotic agents, nefopam (nefopam hy...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Tapentadol is the first US FDA-approved centrally acting analgesic having both μ-opioid receptor agonist and noradrenaline (norepinephrine) reuptake inhibition activity with minimal serotonin reuptake inhibition. Tapentadol is indicated for the manag...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Tapentadol is the first US FDA-approved centrally acting analgesic having both μ-opioid receptor agonist and noradrenaline (norepinephrine) reuptake inhibition activity with minimal serotonin reuptake inhibition. Tapentadol is indicated for the manag...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Tapentadol is the first US FDA-approved centrally acting analgesic having both μ-opioid receptor agonist and noradrenaline (norepinephrine) reuptake inhibition activity with minimal serotonin reuptake inhibition. Tapentadol is indicated for the manag...