OBEVERSEN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Wed Apr 02 11:35:26 GMT 2025` Edited by `admin` on `Wed Apr 02 11:35:26 GMT 2025`
Nucleic Acid Type	OLIGONUCLEOTIDE
Sequence Type	COMPLETE
Record UNII	BX8TS73ATE
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

OBEVERSEN

Official Name

English

DNA, D((2'-O-(2-METHOXYETHYL))M5RU-SP-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))RA-T-SP-T-SP-T-SP-A-SP-A-SP-T-SP-G-SP-A-SP-G-SP-M5C-SP-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M5RU-

Preferred Name

English

obeversen [INN]

Common Name

English

OBEVERSEN [USAN]

Common Name

English

ION-769357 FREE ACID

Code

English

Code System Code Type Description

SMS_ID

300000039924

Created by admin on Wed Apr 02 11:35:26 GMT 2025 , Edited by admin on Wed Apr 02 11:35:26 GMT 2025

PRIMARY

USAN

HI-39

Created by admin on Wed Apr 02 11:35:26 GMT 2025 , Edited by admin on Wed Apr 02 11:35:26 GMT 2025

PRIMARY

NCI_THESAURUS

C186396

Created by admin on Wed Apr 02 11:35:26 GMT 2025 , Edited by admin on Wed Apr 02 11:35:26 GMT 2025

PRIMARY

INN

11911

Created by admin on Wed Apr 02 11:35:26 GMT 2025 , Edited by admin on Wed Apr 02 11:35:26 GMT 2025

PRIMARY

CAS

2304711-30-4

Created by admin on Wed Apr 02 11:35:26 GMT 2025 , Edited by admin on Wed Apr 02 11:35:26 GMT 2025

PRIMARY

FDA UNII

BX8TS73ATE

Created by admin on Wed Apr 02 11:35:26 GMT 2025 , Edited by admin on Wed Apr 02 11:35:26 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
2'-O-Methoxyethyl ribose	1_1-1_5;1_16-1_20	10 / 20
Deoxyribose (DNA)	1_6-1_15	10 / 20

Linkage	Site Range	Site Count
Phosporothioate	1_2;1_7-1_16;1_19-1_20	13 / 19
Phosphate	1_3-1_6;1_17-1_18	6 / 19

Related Record Type Details


					BX8TS73ATE

OBEVERSEN

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOTIDE SUBSTITUTION	[1_1]	5'-TERMINUS			UNSPECIFIED SUBSTANCE	69c9da7b (not in database)
NUCLEOSIDE BASE SUBSTITUTION	[1_3] [1_4] [1_15] [1_18] [1_20]	SITE_SPECIFIC			5-METHYLCYTOSINE	6R795CQT4H
NUCLEOSIDE BASE SUBSTITUTION	[1_1] [1_16] [1_17]	SITE_SPECIFIC		Amount:	THYMINE	QR26YLT7LT