Rilparencel

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NCATS

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 14:55:09 GMT 2025` Edited by `admin` on `Wed Apr 02 14:55:09 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	AUTOLOGOUS HUMAN
Source Materials State	LIVE
Source Materials Parent	`G0T704E6Z3` HOMO SAPIENS WHOLE
Part	kidney; renal cortical tissue
Fraction Name	renal epithelial cells
Record UNII	B72T6TX3GS
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Autologous renal epithelial cells derived from renal cortical tissue via kidney biopsy. The cells are dissociated from the kidney biopsy using enzymatic digestion and then cultured in medium supplemented with several growth factors and cytokines, includi

Preferred Name

English

Rilparencel

Official Name

English

RILPARENCEL [USAN]

Common Name

English

Neo Kidney Augment (NKA)

Common Name

English

rilparencel [INN]

Common Name

English

Renal autologous cell therapy (REACT)

Common Name

English

Code System Code Type Description

USAN

LM-142

Created by admin on Wed Apr 02 14:55:09 GMT 2025 , Edited by admin on Wed Apr 02 14:55:09 GMT 2025

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NCI_THESAURUS

C190422

Created by admin on Wed Apr 02 14:55:09 GMT 2025 , Edited by admin on Wed Apr 02 14:55:09 GMT 2025

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FDA UNII

B72T6TX3GS

Created by admin on Wed Apr 02 14:55:09 GMT 2025 , Edited by admin on Wed Apr 02 14:55:09 GMT 2025

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SMS_ID

300000025656

Created by admin on Wed Apr 02 14:55:09 GMT 2025 , Edited by admin on Wed Apr 02 14:55:09 GMT 2025

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INN

12253

Created by admin on Wed Apr 02 14:55:09 GMT 2025 , Edited by admin on Wed Apr 02 14:55:09 GMT 2025

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Related Record Type Details


					B72T6TX3GS

ACTIVE MOIETY

Comments:

cell therapy (renal tissue regeneration)

Amount:

Agent Modifications

Modification Process	Modification Role	Modification Type	Amount	Fragment Name	Fragment ID
CULTURE	EXPANSION	BIOLOGICAL		NEPIDERMIN	TZK30RF92W
CULTURE	EXPANSION	BIOLOGICAL		INSULIN HUMAN	1Y17CTI5SR
CULTURE	EXPANSION	BIOLOGICAL		HUMAN HEPATOCYTE GROWTH FACTOR	BEI7G52Q8Z
HYPOXIC				Oxygen	S88TT14065

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
ANTIGEN EXPRESSED	BIOLOGICAL		`ZS6J3E8DAS` Keratin, type I cytoskeletal 18

ANTIGEN EXPRESSED	BIOLOGICAL		`LEE6AC7BSF` Glutathione hydrolase 1 proenzyme

ANTIGEN LOW EXPRESSION	BIOLOGICAL		`T23EL69JA5` AQUAPORIN-2 (not present in database)

ANTIGEN NOT EXPRESSED	BIOLOGICAL		`GD0L57IOD9` CELL SURFACE GLYCOPROTEIN MUC18