DescriptionCurator's Comment: The description was created based on several sources, including
https://www.drugbank.ca/drugs/DB00030
Curator's Comment: The description was created based on several sources, including
https://www.drugbank.ca/drugs/DB00030
Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin. Insulin lowers blood glucose levels by stimulating peripheral glucose uptake by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulin inhibits lipolysis in adipocytes, inhibits proteolysis, and enhances protein synthesis.
Human insulin begins to exert its effects within 30 minutes of subcutaneous administration, while peak levels occur 3-4 hours after administration. Due to its quick onset of action, human insulin is considered "bolus insulin" as it provides high levels of insulin in a short period of time to mimic the release of endogenous insulin from the pancreas after meals. Bolus insulin is often combined with once daily, long-acting "basal insulin" to provide low concentrations of background insulin that can keep blood sugar stable between meals or overnight. Use of basal and bolus insulin together is intended to mimic the pancreas' production of endogenous insulin, with a goal of avoiding any periods of hypoglycemia.
CNS Activity
Approval Year
Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 01:01:12 GMT 2023
by
admin
on
Sat Dec 16 01:01:12 GMT 2023
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Protein Type | HORMONE |
Protein Sub Type | INSULINS |
Sequence Origin | HUMAN |
Sequence Type | COMPLETE |
Record UNII |
1Y17CTI5SR
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Record Status |
Validated (UNII)
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Classification Tree | Code System | Code | ||
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WHO-VATC |
QA10AE01
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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WHO-VATC |
QA10AF01
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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CFR |
21 CFR 522.1160
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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NDF-RT |
N0000004931
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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FDA ORPHAN DRUG |
469115
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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WHO-ATC |
A10AE01
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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FDA ORPHAN DRUG |
863821
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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WHO-VATC |
QA10AB01
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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WHO-ATC |
A10AF01
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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NDF-RT |
N0000175944
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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EU-Orphan Drug |
EU/3/15/1532
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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FDA ORPHAN DRUG |
900422
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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WHO-ATC |
A10AB01
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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WHO-VATC |
QA10AD01
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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NCI_THESAURUS |
C581
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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WHO-ATC |
A10AD01
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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NDF-RT |
N0000004931
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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WHO-ATC |
A10AC01
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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NDF-RT |
N0000004931
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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WHO-VATC |
QA10AC01
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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Code System | Code | Type | Description | ||
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234-279-7
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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S-25
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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631657
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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ALTERNATIVE | |||
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9004-10-8
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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GENERIC (FAMILY) | |||
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1Y17CTI5SR
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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CHEMBL1201631
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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C65922
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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SUB128649
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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ALTERNATIVE | |||
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SUB08197MIG
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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SUB25169
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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Insulin
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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CHEMBL2108500
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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SUB25235
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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1Y17CTI5SR
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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SUB25234
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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5931
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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DTXSID7040499
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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11061-68-0
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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CHEMBL2108973
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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253182
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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5012
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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5186
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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CHEMBL2108974
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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DB00030
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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1342106
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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m6293
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | Merck Index | ||
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5003
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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118984375
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY | |||
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100000085442
Created by
admin on Sat Dec 16 01:01:12 GMT 2023 , Edited by admin on Sat Dec 16 01:01:12 GMT 2023
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PRIMARY |
From | To |
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1_7 | 2_7 |
1_19 | 2_20 |
2_6 | 2_11 |
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CONJUGATE -> PARENT |
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SUB_CONCEPT->SUBSTANCE | |||
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BIOSIMILAR -> PARENT |
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ACTIVE MOIETY |
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Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
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Molecular Formula | CHEMICAL |
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MOL_WEIGHT:SEQUENCE | CHEMICAL |
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