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Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 17:21:22 UTC 2021
Edited
by admin
on Sat Jun 26 17:21:22 UTC 2021
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED
Sequence Type COMPLETE
Record UNII
AE72RB1W1X
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ZENOCUTUZUMAB
USAN   INN  
Official Name English
ZENOCUTUZUMAB [USAN]
Common Name English
MCLA128
Code English
IMMUNOGLOBULIN G1, BISPECIFIC, ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTORS, HER2 AND HER3) (HUMANIZED CLONE MCLA-128 .GAMMA.1-CHAIN), DISULFIDE WITH HUMANIZED CLONE MCLA-128 LIGHT CHAIN, DIMER
Systematic Name English
ZENOCUTUZUMAB [WHO-DD]
Common Name English
MCLA-128 (IGG1 BISPECIFIC ANTIBODY WITH ENHANCED ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY (ADCC) ACTIVITY TARGETING HER2 AND HER3 RECEPTORS.)
Common Name English
ZENOCUTUZUMAB [INN]
Common Name English
MCLA-128
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 750020
Created by admin on Sat Jun 26 17:21:22 UTC 2021 , Edited by admin on Sat Jun 26 17:21:22 UTC 2021
NCI_THESAURUS C129822
Created by admin on Sat Jun 26 17:21:22 UTC 2021 , Edited by admin on Sat Jun 26 17:21:22 UTC 2021
Code System Code Type Description
CAS
1969309-56-5
Created by admin on Sat Jun 26 17:21:22 UTC 2021 , Edited by admin on Sat Jun 26 17:21:22 UTC 2021
PRIMARY
NCI_THESAURUS
C152948
Created by admin on Sat Jun 26 17:21:22 UTC 2021 , Edited by admin on Sat Jun 26 17:21:22 UTC 2021
PRIMARY
DRUG BANK
DB15559
Created by admin on Sat Jun 26 17:21:22 UTC 2021 , Edited by admin on Sat Jun 26 17:21:22 UTC 2021
PRIMARY
FDA UNII
AE72RB1W1X
Created by admin on Sat Jun 26 17:21:22 UTC 2021 , Edited by admin on Sat Jun 26 17:21:22 UTC 2021
PRIMARY
INN
10687
Created by admin on Sat Jun 26 17:21:22 UTC 2021 , Edited by admin on Sat Jun 26 17:21:22 UTC 2021
PRIMARY
From To
1_22 1_96
1_151 1_207
1_268 1_328
1_374 1_432
2_22 2_96
2_148 2_204
2_265 2_325
2_371 2_429
1_227 3_214
1_233 2_230
1_236 2_233
2_224 4_214
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN, AFUCOSYLATED
Glycosylation Link Type Site
N 1_304
N 2_301
Related Record Type Details
TARGET -> INHIBITOR
IgG1 bispecific antibody with enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) activity targeting HER2 and HER3 receptors.
TARGET -> INHIBITOR
IgG1 bispecific antibody with enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) activity targeting HER2 and HER3 receptors.
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL