U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

1998
123
Substance Class Protein
Created
by admin
on Mon Mar 31 18:33:07 GMT 2025
Edited
by admin
on Mon Mar 31 18:33:07 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin MOUSE CHIMERIC
Sequence Type COMPLETE
Record UNII
9927MT646M
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BASILIXIMAB
EMA EPAR   INN   MART.   MI   USAN   VANDF   WHO-DD  
INN   USAN  
Official Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN INTERLEUKIN 2 RECEPTOR) (HUMAN-MOUSE MONOCLONAL CHI621 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL CHI621 LIGHT CHAIN, DIMER
Preferred Name English
CHI-621
Code English
basiliximab [INN]
Common Name English
BASILIXIMAB [PURPLE BOOK CDER]
Common Name English
BASILIXIMAB [VANDF]
Common Name English
BASILIXIMAB [MI]
Common Name English
SDZCHI621
Code English
IMMUNOGLOBULIN G1, ANTI-(HUMAN INTERLEUKIN 2 RECEPTOR) (HUMAN-MOUSE MONOCLONAL CHI621 .GAMMA.1-CHAIN), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL CHI621 LIGHT CHAIN, DIMER
Common Name English
Immunoglobulin G1 (human-mouse monoclonal CHI621 heavy chain antihuman interleukin 2 receptor), disulfide with human-mouse monoclonal CHI621 light chain, dimer
Common Name English
SDZ-CHI-621
Code English
BASILIXIMAB [JAN]
Common Name English
IMMUNOGLOBULIN G1 (HUMAN-MOUSE MONOCLONAL CHI621 HEAVY CHAIN ANTIHUMAN INTERLEUKIN 2 RECEPTOR), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL CHI621 LIGHT CHAIN, DIMER
Common Name English
BASILIXIMAB [EMA EPAR]
Common Name English
Basiliximab [WHO-DD]
Common Name English
SIMULECT
Brand Name English
BASILIXIMAB [MART.]
Common Name English
BASILIXIMAB [USAN]
Common Name English
Classification Tree Code System Code
EMA ASSESSMENT REPORTS SIMULECT (AUTHORIZED: GRAFT REJECTION)
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
WHO-ATC L04AC02
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
NDF-RT N0000175621
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
NDF-RT N0000175622
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
NCI_THESAURUS C20401
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
EMA ASSESSMENT REPORTS SIMULECT (AUTHORIZED: KIDNEY TRANSPLATION)
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
NCI_THESAURUS C574
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
FDA ORPHAN DRUG 109197
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
LIVERTOX NBK548587
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
WHO-VATC QL04AC02
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
NDF-RT N0000010279
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
NDF-RT N0000175621
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
Code System Code Type Description
DRUG CENTRAL
4940
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY
MESH
C113157
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY
NCI_THESAURUS
C52186
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY
EVMPD
SUB12468MIG
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY
FDA UNII
9927MT646M
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY
HSDB
8175
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY
SMS_ID
100000092055
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY
WIKIPEDIA
BASILIXIMAB
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY
INN
7578
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY
RXCUI
196102
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY RxNorm
USAN
KK-104
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY
ChEMBL
CHEMBL1201439
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY
LACTMED
Basiliximab
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY
DRUG BANK
DB00074
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY
CAS
179045-86-4
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY
IUPHAR
6879
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY
DAILYMED
9927MT646M
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY
MERCK INDEX
m2273
Created by admin on Mon Mar 31 18:33:07 GMT 2025 , Edited by admin on Mon Mar 31 18:33:07 GMT 2025
PRIMARY Merck Index
From To
1_22 1_96
2_22 2_96
2_144 2_200
2_220 4_211
2_261 2_321
1_144 1_200
2_367 2_425
3_23 3_87
3_131 3_191
4_23 4_87
4_131 4_191
1_220 3_211
1_226 2_226
1_229 2_229
1_261 1_321
1_367 1_425
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_297
N 2_297
Related Record Type Details
ALT-801
TARGET -> INHIBITOR
LOW AFFINITY IMMUNOGLOBULIN .GAMMA. FC REGION RECEPTOR II-B
TARGET -> AGONIST
INTERLEUKIN-2 RECEPTOR SUBUNIT ALPHA
TARGET -> INHIBITOR
HIGH AFFINITY IMMUNOGLOBULIN GAMMA FC RECEPTOR I
TARGET -> AGONIST
Related Record Type Details
BASILIXIMAB
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO_ACID_SUBSTITUTION [1_1] [2_1] N-TERMINUS PIDOLIC ACID SZB83O1W42
AMINO ACID REMOVAL [1_447] [2_447] C-TERMINUS LYSINE K3Z4F929H6
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Biological Half-life PHARMACOKINETIC
Volume of Distribution PHARMACOKINETIC
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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