U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Thu Jul 06 17:16:54 UTC 2023
Edited
by admin
on Thu Jul 06 17:16:54 UTC 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
08TF01H1UT
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
INTERLEUKIN-2 RECEPTOR SUBUNIT ALPHA
Common Name English
IL2RA
Common Name English
IL2-RA
Common Name English
TAC ANTIGEN
Common Name English
P55 (IL-2 RECEPTOR SUBUNIT ALPHA)
Common Name English
INTERLEUKIN 2 RECEPTOR, ALPHA
Common Name English
CD25
Common Name English
Code System Code Type Description
FDA UNII
08TF01H1UT
Created by admin on Thu Jul 06 17:16:55 UTC 2023 , Edited by admin on Thu Jul 06 17:16:55 UTC 2023
PRIMARY
UNIPROT
P01589
Created by admin on Thu Jul 06 17:16:55 UTC 2023 , Edited by admin on Thu Jul 06 17:16:55 UTC 2023
PRIMARY
WIKIPEDIA
CD25
Created by admin on Thu Jul 06 17:16:55 UTC 2023 , Edited by admin on Thu Jul 06 17:16:55 UTC 2023
ALTERNATIVE
From To
1_3 1_147
1_28 1_59
1_30 1_61
1_46 1_104
1_131 1_163
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_49
N 1_68
O 1_197
O 1_203
O 1_208
O 1_216
Related Record Type Details
AGONIST -> TARGET
LIGAND->TARGET
PRECLINICAL
INHIBITOR -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
MODULATOR->TARGET
RO7296682 targets and binds to CD25 expressed on tumor-infiltrating regulatory T (Treg) cells. This may deplete Treg cells and prevent immunosuppression, thereby enhancing anti-tumor immune responses
CONJUGATED TOXIN->TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL