OXOLAMINE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H19N3O
Molecular Weight	245.3202
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN(CC)CCC1=NC(=NO1)C2=CC=CC=C2

InChI

InChIKey=IDCHQQSVJAAUQQ-UHFFFAOYSA-N

InChI=1S/C14H19N3O/c1-3-17(4-2)11-10-13-15-14(16-18-13)12-8-6-5-7-9-12/h5-9H,3-4,10-11H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C14H19N3O
Molecular Weight	245.3202
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ilacprospektusu.com/ilac/619/perebron-10-mg-120-ml-surup | https://www.ncbi.nlm.nih.gov/pubmed/13720535 | https://www.ncbi.nlm.nih.gov/pubmed/7140166

Oxolamine under brand names Symphocal, Perebron is used in some countries as a cough suppressant for the treatment of pharyngitis, tracheitis, bronchitis, bronchiectasis, pertussis. Oxolamine possesses anti-inflammatory activity, which causes a reduction in the irritation of the nervous receptors of the respiratory tract.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Cough 106 Sources: https://www.ilacprospektusu.com/ilac/619/perebron-10-mg-120-ml-surup	Palliative	Approved 8307	Perebron Approved Use Unknown
Tracheitis 3 Sources: https://www.ilacprospektusu.com/ilac/619/perebron-10-mg-120-ml-surup	Palliative	Approved 8307	Perebron Approved Use Unknown
Bronchitis 51 Sources: https://www.ilacprospektusu.com/ilac/619/perebron-10-mg-120-ml-surup	Palliative	Approved 8307	Perebron Approved Use Unknown
Pertussis 3 Sources: https://www.ilacprospektusu.com/ilac/619/perebron-10-mg-120-ml-surup	Palliative	Approved 8307	Perebron Approved Use Unknown

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

In general, 15-25 mg per kilogram per day should be given by dividing four equal doses. In children over 2 years: 1-2 ml of 5 ml Adults: 2 ml of 5 ml 4 times daily 4 hours a day, after an equal amount of water.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sun Dec 18 21:03:24 UTC 2022` Edited by `admin` on `Sun Dec 18 21:03:24 UTC 2022`
Record UNII	90BEA145GY
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

OXOLAMINE

Official Name

English

5-(2-(DIETHYLAMINO)ETHYL)-3-PHENYL-1,2,4-OXADIAZOLE

Systematic Name

English

OKSALAMIN

Brand Name

English

OXOLAMINE [MI]

Common Name

English

SKF-9976 FREE BASE

Code

English

Oxolamine [WHO-DD]

Common Name

English

OXOLAMINE [MART.]

Common Name

English

oxolamine [INN]

Common Name

English

AF-438 FREE BASE

Code

English

SKF 9976 FREE BASE

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C257