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Details

Stereochemistry ACHIRAL
Molecular Formula F.Na
Molecular Weight 41.9882
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Sodium fluoride

SMILES

[F-].[Na+]

InChI

InChIKey=PUZPDOWCWNUUKD-UHFFFAOYSA-M
InChI=1S/FH.Na/h1H;/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula FH
Molecular Weight 20.0063
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.drugs.com/international/olaflur.html | https://www.ncbi.nlm.nih.gov/pubmed/15528912 | https://clinicaltrials.gov/ct2/show/record/NCT00268138 | https://www.old.health.gov.il/units/pharmacy/trufot/alonim/4872.pdf

Oleylamine (or oleamine) is a versatile and flexible reagent in synthesis as well as the desired surface ligand for the synthesis of nanoparticles. This compound is rather toxic to mammalian organism.

CNS Activity

Originator

Sources: Helvetica Odontologica Acta (1962), 6, (1), 15-20.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
elmex

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
An improved method for emergent decontamination of ocular and dermal hydrofluoric acid splashes.
2004 Aug
Successful extracorporeal life support after potentially fatal pulmonary oedema caused by inhalation of nitric and hydrofluoric acid fumes.
2007 Oct
Oleylamine as a beneficial agent for the synthesis of CoFe₂O₄ nanoparticles with potential biomedical uses.
2014 May 7
Cytotoxicity of organic surface coating agents used for nanoparticles synthesis and stability.
2015 Jun
Allergic contact cheilitis caused by olaflur in toothpaste.
2017 Jan
Patents

Patents

Sample Use Guides

Brushing your teeth thoroughly with the preparation once a week. Just use elmex dental gel using a regular toothbrush for a period of 2-3 minutes, rinse normally. The total time of application (brushing and residence time) should not exceed five minutes.
Route of Administration: Dental
In Vitro Use Guide
The outer 50-100 mkm of the surface of freshly extracted human incisors was removed by grinding and polishing, thus removing not only the pellicle from the surface but also the outer mineral layer, which in general shows the greatest variation in chemical constituents. Amine fluoride 297 (AmF 297) were dissolved in distilled water. After adsorption of aminefluorides on the enamel for 2 min at a volume to area ratio of 25 cm3/cm2, the enamel surfaces were rinsed with distilled water and allowed to dry for several hours at room temperature in an enclosed chamber. Subsequently adsorbed layer thicknesses were determined by ellipsometry, and surface free energies were calculated from contact angle data.
Substance Class Chemical
Created
by admin
on Sat Dec 16 20:10:39 GMT 2023
Edited
by admin
on Sat Dec 16 20:10:39 GMT 2023
Record UNII
8ZYQ1474W7
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Sodium fluoride
DASH   EP   HSDB   INCI   ISO   JAN   MART.   MI   ORANGE BOOK   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
INCI  
Official Name English
NSC-77385
Code English
DENTALFLUORO
Common Name English
COLGATE TOTAL COMPONENT SODIUM FLUORIDE
Common Name English
NATRUM FLUORATUM
HPUS  
Common Name English
SODIUM FLUORIDE [ISO]
Common Name English
FLUORIDE (AS SODIUM) [VANDF]
Common Name English
NATRII FLUORIDUM [WHO-IP LATIN]
Common Name English
SODIUM FLUORIDE [ORANGE BOOK]
Common Name English
SODIUM FLUORIDE [VANDF]
Common Name English
SODIUM FLUORIDE [USP MONOGRAPH]
Common Name English
SODIUM FLUORIDE [MI]
Common Name English
SODIUM FLUORIDE [JAN]
Common Name English
SODIUM FLUORIDE [HSDB]
Common Name English
SODIUM FLUORIDE [EP MONOGRAPH]
Common Name English
SODIUM FLUORIDE (NAF)
Common Name English
SODIUM FLUORIDE [WHO-IP]
Common Name English
Sodium fluoride [WHO-DD]
Common Name English
PERGANTENE
Common Name English
NATRUM FLUORATUM [HPUS]
Common Name English
FLUORIDE (AS SODIUM FLUORIDE) [VANDF]
Common Name English
SODIUM FLUORIDE [USP-RS]
Common Name English
SODIUM FLUORIDE COMPONENT OF COLGATE TOTAL
Common Name English
SODIUM FLUORIDE [INCI]
Common Name English
NEUTRAL SODIUM FLUORIDE
Brand Name English
SODIUM FLUORIDE [MART.]
Common Name English
Classification Tree Code System Code
WHO-ATC A01AA51
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
WHO-ESSENTIAL MEDICINES LIST 27
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
CFR 21 CFR 355.70
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
WHO-VATC QA01AA01
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
EPA PESTICIDE CODE 75202
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
WHO-ATC A12CD01
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
WHO-VATC QA12CD01
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
CFR 21 CFR 355.60
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
CFR 21 CFR 355.20
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
WHO-ATC A01AA01
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
CFR 21 CFR 355.10
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
CFR 21 CFR 355.50
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
CFR 21 CFR 355.55
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
NCI_THESAURUS C802
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
Code System Code Type Description
ChEMBL
CHEMBL1528
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
MERCK INDEX
m10024
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY Merck Index
WIKIPEDIA
Fluoride therapy
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
RS_ITEM_NUM
1614002
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
NCI_THESAURUS
C832
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
CHEBI
28741
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
CAS
7681-49-4
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
MESH
D012969
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
WIKIPEDIA
SODIUM FLUORIDE
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
EVMPD
SUB15285MIG
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
FDA UNII
8ZYQ1474W7
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
SMS_ID
100000091554
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
HSDB
1766
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
EPA CompTox
DTXSID2020630
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
DRUG CENTRAL
4243
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
PUBCHEM
5235
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
DAILYMED
8ZYQ1474W7
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
ALANWOOD
sodium fluoride
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
ECHA (EC/EINECS)
231-667-8
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
RXCUI
9873
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY RxNorm
DRUG BANK
DB09325
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
NSC
77385
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
SODIUM FLUORIDE
Created by admin on Sat Dec 16 20:10:39 GMT 2023 , Edited by admin on Sat Dec 16 20:10:39 GMT 2023
PRIMARY Description: A white powder; odourless. Solubility: Soluble in water; practically insoluble in ethanol (~750 g/l) TS. Category: Mineral salt. Storage: Sodium fluoride should be kept in a well-closed container. Definition: Sodium fluoride contains not less than 98.0% and not more than 101.0% of NaF, calculated with reference to the dried substance.
Related Record Type Details
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY