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Details

Stereochemistry ACHIRAL
Molecular Formula C18H18F3NO2
Molecular Weight 337.3362
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of UFENAMATE

SMILES

CCCCOC(=O)C1=C(NC2=CC=CC(=C2)C(F)(F)F)C=CC=C1

InChI

InChIKey=JDLSRXWHEBFHNC-UHFFFAOYSA-N
InChI=1S/C18H18F3NO2/c1-2-3-11-24-17(23)15-9-4-5-10-16(15)22-14-8-6-7-13(12-14)18(19,20)21/h4-10,12,22H,2-3,11H2,1H3

HIDE SMILES / InChI

Molecular Formula C18H18F3NO2
Molecular Weight 337.3362
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Ufenamate is a topical analgesic. It is indicated for pain and inflammation associated with musculoskeletal and joint disorders. It is a COX inhibitor. Ufenamate is freely soluble in oil and is poorly soluble in water. It is used in the form of ointments or creams. It is manufactured under the brand name Combec in Japan. It is also an ingredient of Fenazol Ointment 5%, used in Japan for the treatment of eczema, dermatitis and herpes zoster.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Fenazol Ointment 5%
Primary
Fenazol Ointment 5%
Primary
Fenazol Ointment 5%

PubMed

Sample Use Guides

In Vivo Use Guide
Apply as a topical preparation at 3% or 3.5%.
Route of Administration: Topical
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
8Z7O7C1SLZ
Record Status Validated (UNII)
Record Version