DEACETYLDILTIAZEM

COC1=CC=C(C=C1)[C@@H]2SC3=CC=CC=C3N(CCN(C)C)C(=O)[C@@H]2O

InChIKey=NZHUXMZTSSZXSB-MOPGFXCFSA-N

InChI=1S/C20H24N2O3S/c1-21(2)12-13-22-16-6-4-5-7-17(16)26-19(18(23)20(22)24)14-8-10-15(25-3)11-9-14/h4-11,18-19,23H,12-13H2,1-3H3/t18-,19+/m1/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

PubMed

Title	Date	PubMed
Effect of diltiazem and low-dose aspirin on platelet aggregation and ATP release induced by paired agonists.	1993 Aug 2	8236144
Anaphylatoxin C3a induces rapid protein phosphorylation in guinea pig platelets.	1994 Sep-Oct	8002292
Ca2+ channel blockers modulate metabolism of collagens within the extracellular matrix.	1996 May 28	8643600
Effects of diltiazem on down-regulation of lymphocyte beta-adrenoceptors in patients with chronic congestive heart failure.	2000 Oct	11501046
Pharmacokinetic interaction between tacrolimus and diltiazem: dose-response relationship in kidney and liver transplant recipients.	2002	12036394

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:17:11 UTC 2023` Edited by `admin` on `Fri Dec 15 16:17:11 UTC 2023`
Record UNII	849UT193YJ
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

DEACETYLDILTIAZEM

Common Name

English

DILTIAZEM HYDROCHLORIDE IMPURITY F [EP IMPURITY]

Common Name

English

1,5-BENZOTHIAZEPIN-4(5H)-ONE, 5-(2-(DIMETHYLAMINO)ETHYL)-2,3-DIHYDRO-3-HYDROXY-2-(4-METHOXYPHENYL)-, (2S,3S)-

Systematic Name

English

(+)-DESACETYLDILTIAZEM

Common Name

English

DEACETYL-D-DILTIAZEM

Common Name

English

Desacetyldiltiazem [WHO-DD]

Common Name

English

DESACETYLDILTIAZEM [WHO-IP]

Common Name

English

DESACETYLDILTIAZEM

Common Name

English

Code System Code Type Description

PUBCHEM

91638