DEACETYLDILTIAZEM

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H24N2O3S
Molecular Weight	372.481
Optical Activity	( + )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DEACETYLDILTIAZEM

Structure Search

SMILES

COC1=CC=C(C=C1)[C@@H]2SC3=CC=CC=C3N(CCN(C)C)C(=O)[C@@H]2O

InChI

InChIKey=NZHUXMZTSSZXSB-MOPGFXCFSA-N

InChI=1S/C20H24N2O3S/c1-21(2)12-13-22-16-6-4-5-7-17(16)26-19(18(23)20(22)24)14-8-10-15(25-3)11-9-14/h4-11,18-19,23H,12-13H2,1-3H3/t18-,19+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C20H24N2O3S
Molecular Weight	372.481
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

PubMed

Title	Date	PubMed
The influence of diltiazem versus cimetidine on propranolol metabolism.	1992 Dec	1487547
Slowing the progression of renal disease in diabetic patients.	2001 Apr	11302410
The role of calcium antagonists in chronic kidney disease.	2004 Mar	15202609

Patents

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:17:11 GMT 2023` Edited by `admin` on `Fri Dec 15 16:17:11 GMT 2023`
Record UNII	849UT193YJ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DEACETYLDILTIAZEM

Common Name

English

DILTIAZEM HYDROCHLORIDE IMPURITY F [EP IMPURITY]

Common Name

English

1,5-BENZOTHIAZEPIN-4(5H)-ONE, 5-(2-(DIMETHYLAMINO)ETHYL)-2,3-DIHYDRO-3-HYDROXY-2-(4-METHOXYPHENYL)-, (2S,3S)-

Systematic Name

English

(+)-DESACETYLDILTIAZEM

Common Name

English

DEACETYL-D-DILTIAZEM

Common Name

English

Desacetyldiltiazem [WHO-DD]

Common Name

English

DESACETYLDILTIAZEM [WHO-IP]

Common Name

English

DESACETYLDILTIAZEM

Common Name

English

Code System Code Type Description

PUBCHEM

91638

Created by admin on Fri Dec 15 16:17:11 GMT 2023 , Edited by admin on Fri Dec 15 16:17:11 GMT 2023

PRIMARY

EVMPD

SUB112491

Created by admin on Fri Dec 15 16:17:11 GMT 2023 , Edited by admin on Fri Dec 15 16:17:11 GMT 2023

PRIMARY

MESH

C037769

Created by admin on Fri Dec 15 16:17:11 GMT 2023 , Edited by admin on Fri Dec 15 16:17:11 GMT 2023

PRIMARY

CAS

91602-22-1

Created by admin on Fri Dec 15 16:17:11 GMT 2023 , Edited by admin on Fri Dec 15 16:17:11 GMT 2023

SUPERSEDED

SMS_ID

100000142066

Created by admin on Fri Dec 15 16:17:11 GMT 2023 , Edited by admin on Fri Dec 15 16:17:11 GMT 2023

PRIMARY

CAS

42399-40-6

Created by admin on Fri Dec 15 16:17:11 GMT 2023 , Edited by admin on Fri Dec 15 16:17:11 GMT 2023

PRIMARY

ECHA (EC/EINECS)

255-795-9

Created by admin on Fri Dec 15 16:17:11 GMT 2023 , Edited by admin on Fri Dec 15 16:17:11 GMT 2023

PRIMARY

EPA CompTox

DTXSID00881093

Created by admin on Fri Dec 15 16:17:11 GMT 2023 , Edited by admin on Fri Dec 15 16:17:11 GMT 2023

PRIMARY

FDA UNII

849UT193YJ

Created by admin on Fri Dec 15 16:17:11 GMT 2023 , Edited by admin on Fri Dec 15 16:17:11 GMT 2023

PRIMARY

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					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Amount:


					ZQ8A4H7BT3

DEACETYLDILTIAZEM HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:

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DILTIAZEM

PARENT -> METABOLITE

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DILTIAZEM HYDROCHLORIDE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount: