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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H24N2O3S
Molecular Weight 372.481
Optical Activity ( + )
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DEACETYLDILTIAZEM

SMILES

COC1=CC=C(C=C1)[C@@H]2SC3=CC=CC=C3N(CCN(C)C)C(=O)[C@@H]2O

InChI

InChIKey=NZHUXMZTSSZXSB-MOPGFXCFSA-N
InChI=1S/C20H24N2O3S/c1-21(2)12-13-22-16-6-4-5-7-17(16)26-19(18(23)20(22)24)14-8-10-15(25-3)11-9-14/h4-11,18-19,23H,12-13H2,1-3H3/t18-,19+/m1/s1

HIDE SMILES / InChI

Molecular Formula C20H24N2O3S
Molecular Weight 372.481
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Anaphylatoxin C3a induces rapid protein phosphorylation in guinea pig platelets.
1994 Sep-Oct
Inhibitory effects of TA-993, a new 1,5-benzothiazepine derivative, on platelet aggregation.
1996 Apr
Relative bioavailability of Cardizem CD and Tiazac controlled-release diltiazem dosage forms after single and multiple dosing in healthy volunteers.
1998 May
The effect of calcium channel blockers on cerebral oxygenation during tracheal extubation.
2000 Aug
Effects of diltiazem retard on ambulatory blood pressure and heart rate variability in patients with essential hypertension.
2000 Jun
Slowing the progression of renal disease in diabetic patients.
2001 Apr
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 16:17:11 UTC 2023
Edited
by admin
on Fri Dec 15 16:17:11 UTC 2023
Record UNII
849UT193YJ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DEACETYLDILTIAZEM
Common Name English
DILTIAZEM HYDROCHLORIDE IMPURITY F [EP IMPURITY]
Common Name English
1,5-BENZOTHIAZEPIN-4(5H)-ONE, 5-(2-(DIMETHYLAMINO)ETHYL)-2,3-DIHYDRO-3-HYDROXY-2-(4-METHOXYPHENYL)-, (2S,3S)-
Systematic Name English
(+)-DESACETYLDILTIAZEM
Common Name English
DEACETYL-D-DILTIAZEM
Common Name English
Desacetyldiltiazem [WHO-DD]
Common Name English
DESACETYLDILTIAZEM [WHO-IP]
Common Name English
DESACETYLDILTIAZEM
WHO-DD  
Common Name English
Code System Code Type Description
PUBCHEM
91638
Created by admin on Fri Dec 15 16:17:11 UTC 2023 , Edited by admin on Fri Dec 15 16:17:11 UTC 2023
PRIMARY
EVMPD
SUB112491
Created by admin on Fri Dec 15 16:17:11 UTC 2023 , Edited by admin on Fri Dec 15 16:17:11 UTC 2023
PRIMARY
MESH
C037769
Created by admin on Fri Dec 15 16:17:11 UTC 2023 , Edited by admin on Fri Dec 15 16:17:11 UTC 2023
PRIMARY
CAS
91602-22-1
Created by admin on Fri Dec 15 16:17:11 UTC 2023 , Edited by admin on Fri Dec 15 16:17:11 UTC 2023
SUPERSEDED
SMS_ID
100000142066
Created by admin on Fri Dec 15 16:17:11 UTC 2023 , Edited by admin on Fri Dec 15 16:17:11 UTC 2023
PRIMARY
CAS
42399-40-6
Created by admin on Fri Dec 15 16:17:11 UTC 2023 , Edited by admin on Fri Dec 15 16:17:11 UTC 2023
PRIMARY
ECHA (EC/EINECS)
255-795-9
Created by admin on Fri Dec 15 16:17:11 UTC 2023 , Edited by admin on Fri Dec 15 16:17:11 UTC 2023
PRIMARY
EPA CompTox
DTXSID00881093
Created by admin on Fri Dec 15 16:17:11 UTC 2023 , Edited by admin on Fri Dec 15 16:17:11 UTC 2023
PRIMARY
FDA UNII
849UT193YJ
Created by admin on Fri Dec 15 16:17:11 UTC 2023 , Edited by admin on Fri Dec 15 16:17:11 UTC 2023
PRIMARY
Related Record Type Details
BINDER->LIGAND
SALT/SOLVATE -> PARENT
Related Record Type Details
PARENT -> METABOLITE
Related Record Type Details
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP