DEACETYLDILTIAZEM HYDROCHLORIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H24N2O3S.ClH
Molecular Weight	408.942
Optical Activity	( + )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DEACETYLDILTIAZEM HYDROCHLORIDE

Structure Search

SMILES

Cl.COC1=CC=C(C=C1)[C@@H]2SC3=CC=CC=C3N(CCN(C)C)C(=O)[C@@H]2O

InChI

InChIKey=XNQWAVFYFJXSHD-VOMIJIAVSA-N

InChI=1S/C20H24N2O3S.ClH/c1-21(2)12-13-22-16-6-4-5-7-17(16)26-19(18(23)20(22)24)14-8-10-15(25-3)11-9-14;/h4-11,18-19,23H,12-13H2,1-3H3;1H/t18-,19+;/m1./s1

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C20H24N2O3S
Molecular Weight	372.481
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
The influence of diltiazem versus cimetidine on propranolol metabolism.	1992 Dec	1487547
Effects of diltiazem on down-regulation of lymphocyte beta-adrenoceptors in patients with chronic congestive heart failure.	2000 Oct	11501046
Pharmacokinetic interaction between tacrolimus and diltiazem: dose-response relationship in kidney and liver transplant recipients.	2002	12036394

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 12:01:31 GMT 2023` Edited by `admin` on `Sat Dec 16 12:01:31 GMT 2023`
Record UNII	ZQ8A4H7BT3
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DEACETYLDILTIAZEM HYDROCHLORIDE

Common Name

English

(2S-CIS)-5-(2-(DIMETHYLAMINO)ETHYL)-2,3-DIHYDRO-3-HYDROXY-2-(4-METHOXYPHENYL)-1,5-BENZOTHIAZEPIN-4(5H)-ONE MONOHYDROCHLORIDE

Systematic Name

English

DESACETYLDILTIAZEM HYDROCHLORIDE

Common Name

English

1,5-BENZOTHIAZEPIN-4(5H)-ONE, 5-(2-(DIMETHYLAMINO)ETHYL)-2,3-DIHYDRO-3-HYDROXY-2-(4-METHOXYPHENYL)-, MONOHYDROCHLORIDE, (2S,3S)-

Systematic Name

English

1,5-BENZOTHIAZEPIN-4(5H)-ONE, 5-(2-(DIMETHYLAMINO)ETHYL)-2,3-DIHYDRO-3-HYDROXY-2-(4-METHOXYPHENYL)-, HYDROCHLORIDE (1:1), (2S,3S)-

Systematic Name

English

Code System Code Type Description

FDA UNII

ZQ8A4H7BT3