U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C15H11ClFN5
Molecular Weight 315.733
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of IMARADENANT

SMILES

CC1=NC(Cl)=CC(=C1)C2=NN=C(N)N=C2C3=CC=C(F)C=C3

InChI

InChIKey=NCWQLHHDGDXIJN-UHFFFAOYSA-N
InChI=1S/C15H11ClFN5/c1-8-6-10(7-12(16)19-8)14-13(20-15(18)22-21-14)9-2-4-11(17)5-3-9/h2-7H,1H3,(H2,18,20,22)

HIDE SMILES / InChI

Molecular Formula C15H11ClFN5
Molecular Weight 315.733
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: P29274
Gene ID: 135.0
Gene Symbol: ADORA2A
Target Organism: Homo sapiens (Human)
1.7 nM [Ki]
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:26:23 GMT 2023
Edited
by admin
on Sat Dec 16 08:26:23 GMT 2023
Record UNII
770140J08A
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IMARADENANT
INN  
Official Name English
AZD-4635
Code English
HTL1071
Code English
Imaradenant [WHO-DD]
Common Name English
6-(2-CHLORO-6-METHYLPYRIDIN-4-YL)-5-(4-FLUOROPHENYL)-1,2,4-TRIAZIN-3-AMINE
Systematic Name English
imaradenant [INN]
Common Name English
HTL-1071
Code English
1,2,4-TRIAZIN-3-AMINE, 6-(2-CHLORO-6-METHYL-4-PYRIDINYL)-5-(4-FLUOROPHENYL)-
Systematic Name English
AZD4635
Code English
Code System Code Type Description
INN
11244
Created by admin on Sat Dec 16 08:26:23 GMT 2023 , Edited by admin on Sat Dec 16 08:26:23 GMT 2023
PRIMARY
PUBCHEM
86676119
Created by admin on Sat Dec 16 08:26:23 GMT 2023 , Edited by admin on Sat Dec 16 08:26:23 GMT 2023
PRIMARY
NCI_THESAURUS
C148039
Created by admin on Sat Dec 16 08:26:23 GMT 2023 , Edited by admin on Sat Dec 16 08:26:23 GMT 2023
PRIMARY
CAS
1321514-06-0
Created by admin on Sat Dec 16 08:26:23 GMT 2023 , Edited by admin on Sat Dec 16 08:26:23 GMT 2023
PRIMARY
FDA UNII
770140J08A
Created by admin on Sat Dec 16 08:26:23 GMT 2023 , Edited by admin on Sat Dec 16 08:26:23 GMT 2023
PRIMARY
SMS_ID
300000023901
Created by admin on Sat Dec 16 08:26:23 GMT 2023 , Edited by admin on Sat Dec 16 08:26:23 GMT 2023
PRIMARY
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