FELZARTAMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 15:17:17 GMT 2023` Edited by `admin` on `Sat Dec 16 15:17:17 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	3O9FA4XC02
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FELZARTAMAB

Official Name

English

ANTI-CD38 MONOCLONAL ANTIBODY MOR03087

Common Name

English

TJ-202

Code

English

TJ202

Code

English

MOR202

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN CD38 ANTIGEN) (HUMAN MONOCLONAL MOR03087 .GAMMA.-1 CHAIN), DISULFIDE WITH HUMAN MONOCLONAL MOR03087 .LAMBDA.-CHAIN, DIMER

Common Name

English

Felzartamab [WHO-DD]

Common Name

English

MOR-202

Code

English

MOR03087

Code

English

felzartamab [INN]

Common Name

English

MOR-03087

Code

English

IMMUNOGLOBULIN G1-LAMBDA, ANTI-(HOMO SAPIENS CD38 (ADP-RIBOSYL CYCLASE 1, CYCLIC ADP-RIBOSE HYDROLASE 1, CADPR HYDROLASE 1, T10)), HUMANIZED MONOCLONAL ANTIBODY

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

939423

Created by admin on Sat Dec 16 15:17:17 GMT 2023 , Edited by admin on Sat Dec 16 15:17:17 GMT 2023

Code System Code Type Description

INN

11074

Created by admin on Sat Dec 16 15:17:17 GMT 2023 , Edited by admin on Sat Dec 16 15:17:17 GMT 2023

PRIMARY

FDA UNII

3O9FA4XC02

Created by admin on Sat Dec 16 15:17:17 GMT 2023 , Edited by admin on Sat Dec 16 15:17:17 GMT 2023

PRIMARY

CAS

2197112-39-1

Created by admin on Sat Dec 16 15:17:17 GMT 2023 , Edited by admin on Sat Dec 16 15:17:17 GMT 2023

PRIMARY

NCI_THESAURUS

C97954

Created by admin on Sat Dec 16 15:17:17 GMT 2023 , Edited by admin on Sat Dec 16 15:17:17 GMT 2023

PRIMARY

From	To
1_22	1_96
1_147	1_203
1_223	3_212
1_229	2_229
1_232	2_232
1_264	1_324
1_370	1_428
2_22	2_96
2_147	2_203
2_223	4_212
2_264	2_324
2_370	2_428
3_22	3_87
3_135	3_194
4_22	4_87
4_135	4_194

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_300
N	2_300

Related Record Type Details


					JMN849I3XV

ADP-RIBOSYL CYCLASE/CYCLIC ADP-RIBOSE HYDROLASE 1

TARGET -> INHIBITOR

Comments:

ADCC and ADCP are considered to be primary modes of action for MOR202 targeting CD38 high expressing cells.

Qualification:

EC50

Amount:

Related Record Type Details


					3O9FA4XC02

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL